Substance / Medication

Clemastine

Overview

Active Ingredient
clemastine
RxNorm CUI
2578

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Evaluation of Pharmacological Treatments for Acute Urticaria: A Systematic Review and Meta-Analysis.
Jamjanya Sirinda, Danpanichkul Pojsakorn, Ongsupankul Sorawit et al. · J Allergy Clin Immunol Pract · 2024
PMID: 38280453Meta-Analysis
Efficacy and Safety of Systemic Corticosteroids for Urticaria: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Chu Xiajing, Wang Jason, Ologundudu Leonardo et al. · J Allergy Clin Immunol Pract · 2024
PMID: 38642709Meta-Analysis
Effect of the H-antihistamine clemastine on PACAP38 induced migraine.
Vollesen Luise Haulund, Guo Song, Andersen Malene Rohr et al. · Cephalalgia · 2019
PMID: 30165750RCT
Clemastine fumarate accelerates accumulation of disability in progressive multiple sclerosis by enhancing pyroptosis.
Kocot Joanna, Kosa Peter, Ashida Shinji et al. · J Clin Invest · 2025
PMID: 40371642TrialFull text (PMC)
Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase-dependent proinflammatory cytokines.
Johansen Pål, Weiss Andreas, Bünter Antonia et al. · J Allergy Clin Immunol · 2011
PMID: 21807405Trial
Clinical pharmacology of clemastine in healthy dogs.
Hansson H, Bergvall K, Bondesson U et al. · Vet Dermatol · 2004
PMID: 15214951Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clemastine (substance)
SNOMED CT
372744005
UMLS CUI
C0008929
RxNorm CUI
2578

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.