Substance / Medication

Clobetasol propionate

SNOMED 32197004 UMLS C0055895

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Dermatosis of scalp

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Efficacy and safety of topical clobetasol propionate in comparison with alternative treatments in oral lichen planus: an updated systematic review and meta-analysis.

Zheng Tao, Liu ChengYong, Wang YeTong et al. · Front Med (Lausanne) · 2024

PMID: 38854667Meta-AnalysisFull text (PMC)

Topical clobetasol propionate in the treatment of psoriasis: a review of newer formulations.

Feldman Steven R, Yentzer Brad A · Am J Clin Dermatol · 2009

PMID: 19824740Meta-Analysis

Evaluation of the efficacy of supplementary probiotic capsules with topical clobetasol propionate 0.05% versus topical clobetasol propionate 0.05% in the treatment of oral lichen planus (a randomized clinical trial).

Kamal Yasmine, Abdelwhab Amira, Salem Sherifa Tarek et al. · BMC Oral Health · 2025

PMID: 40045332RCTFull text (PMC)

Comparative evaluation of the efficacy of Nigella sativa (75% v/v) cream and clobetasol propionate (0.05% w/w) gel in oral lichen planus-a double-blinded randomized control trial.

Kumar S Lokesh, Naik Zameera, Panwar Arun et al. · Oral Maxillofac Surg · 2024

PMID: 36547822RCT

The Effect of Lipofilling and Platelet-Rich Plasma on Patients with Moderate-Severe Vulvar Lichen Sclerosus who were Non-Responders to Topical Clobetasol Propionate: A Randomized Pilot Study.

Gutierrez-Ontalvilla P, Giner F, Vidal L et al. · Aesthetic Plast Surg · 2022

PMID: 35048150RCT

The comparison of therapeutic effect of Clobetasol propionate lotion and squill extract in alopecia areata: a randomized, double-blind clinical trial.

Moosavi Zahra Beygom, Aliabdi Maryam, Golfakhrabadi Fereshteh et al. · Arch Dermatol Res · 2020

PMID: 31707498RCT

Randomized, placebo-controlled, double-blind trial of clobetasol propionate 0.05% in the treatment of oral lichen planus.

Arduino P G, Campolongo M G, Sciannameo V et al. · Oral Dis · 2018

PMID: 29297958RCT

Clobetasol propionate vs. mometasone furoate in 1-year proactive maintenance therapy of vulvar lichen sclerosus: results from a comparative trial.

Corazza M, Borghi A, Minghetti S et al. · J Eur Acad Dermatol Venereol · 2016

PMID: 25904498RCT

Topical delivery of clobetasol propionate loaded microemulsion based gel for effective treatment of vitiligo--part II: rheological characterization and in vivo assessment through dermatopharmacokinetic and pilot clinical studies.

Patel Hetal K, Barot Bhavesh S, Parejiya Punit B et al. · Colloids Surf B Biointerfaces · 2014

PMID: 24767976RCT

A comparative study in efficacy and safety of 0.1% tacrolimus and 0.05% clobetasol propionate ointment in discoid lupus erythematosus by modified cutaneous lupus erythematosus disease area and severity index.

Pothinamthong Pornchai, Janjumratsang Patcharin · J Med Assoc Thai · 2012

PMID: 22919989RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Clobetasol propionate (substance)
SNOMED CT: 32197004
UMLS CUI: C0055895

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.