Substance / Medication

Clofibrate

Overview

Active Ingredient
clofibrate
RxNorm CUI
2594

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

20 trials linked to this intervention

20
Total Trials
0
Recruiting
10
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia.
Gholitabar Maryam, McGuire Hugh, Rennie Janet et al. · Cochrane Database Syst Rev · 2012
PMID: 23235669Meta-AnalysisFull text (PMC)
Clofibrate for unconjugated hyperbilirubinemia in neonates: a systematic review.
Xiong Tao, Chen Dapeng, Duan Zhoujin et al. · Indian Pediatr · 2012
PMID: 22318100Meta-Analysis
Clofibrate increases long-chain fatty acid oxidation by neonatal pigs.
Bai Xiumei, Lin Xi, Drayton Josephine et al. · J Nutr · 2014
PMID: 25332467RCT
The effect of clofibrate on hyperbilirubinemia of term neonates.
Habibi Morteza, Mahyar Abolfazl, Ayazi Parviz et al. · Acta Med Iran · 2012
PMID: 22267374RCT
Single dose of 50 mg/kg clofibrate in jaundice of healthy term neonates: randomised clinical trial of efficacy and safety.
Fallah Razieh, Islami Zia, Lotfi Saeid Reza · Indian J Pediatr · 2012
PMID: 21785863RCT
The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice.
Sakha Sedigheh Hossein Pour, Gharehbaghi Manizheh Mostafa, Rahbani Mohammad Ebrahim · Indian J Med Sci · 2009
PMID: 19584487RCT
Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial).
Zahedpasha Yadollah, Ahmadpour-Kacho Mousa, Hajiahmadi Mahmood et al. · Southeast Asian J Trop Med Public Health · 2008
PMID: 18564698RCT
Effect of clofibrate in non-hemolytic indirect hyperbiliru-binemia in full term neonates.
Eghbalian Fatemeh, Pourhossein Abolfazl, Zandevakili Hassan · Indian J Pediatr · 2007
PMID: 18057680RCT
Effects of clofibrate treatment in laying hens.
König B, Kluge H, Haase K et al. · Poult Sci · 2007
PMID: 17495091RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clofibrate (substance)
SNOMED CT
387439004
UMLS CUI
C0009002
RxNorm CUI
2594

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
20
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.