Substance / Medication

Clonidine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

156 trials linked to this intervention

156
Total Trials
17
Recruiting
59
With Results

Research Evidence

Published studies and systematic reviews

Sort:
[Antipsychotic Treatment of Alcohol Withdrawal Syndrome with Focus on Delirium Tremens: a Systematic Review].
Faustmann Timo Jendrik, Paschali Myrella, Kojda Georg et al. · Fortschr Neurol Psychiatr · 2025
PMID: 36958342Meta-Analysis
Onabotulinum Toxin A (BoNT-A) for Drooling in Children: A Systematic Review and Meta-Analysis.
Oad Haresh, Maltezeanu Alix, da Silva Sabrina D et al. · Laryngoscope · 2024
PMID: 38294288Meta-Analysis
Effectiveness of atropine in managing sialorrhea: A systematic review and meta-analysis.
Yellepeddi Venkata K, Race Jonathan A, McFarland Mary M et al. · Int J Clin Pharmacol Ther · 2024
PMID: 38577753Meta-Analysis
Management of sialorrhea in children: a systematic review.
Vasconcelos Manuela Leitão de, Cunha Divany Guedes Pereira da, Alves Giorvan Ânderson Dos Santos et al. · Rev Assoc Med Bras (1992) · 2024
PMID: 38655996Meta-AnalysisFull text (PMC)
A systematic review of the perspectives of botulinum toxin use on the quality of life of neurological patients with drooling.
Silva Michelle Almeida, da Silveira Márcia Maria Fonseca, Pedrosa Bruna Rafaele Vieira et al. · Clin Oral Investig · 2024
PMID: 38758415Meta-Analysis
Outcome of kinesio taping in drooling children: A systematic review.
Saniasiaya Jeyasakthy, van der Meer Graeme, Toll Ed C · Int J Pediatr Otorhinolaryngol · 2024
PMID: 39121685Meta-Analysis
Effectiveness of the pharmacological treatments for sialorrhea in patients with Parkinson's disease: a systematic review and network meta-analysis.
Santos Junior Luiz Carlos, Santos José Ronaldo, Reis Alessandra et al. · Clin Oral Investig · 2023
PMID: 37036514Meta-Analysis
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials.
Fornaro Michele, Caiazza Claudio, Solini Niccolò et al. · Mol Psychiatry · 2023
PMID: 37821573Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clonidine hydrochloride (substance)
SNOMED CT
387121001
UMLS CUI
C0546860

Clinical Data

This intervention maps to 12 entities in the Ltrl knowledge graph.

9
Conditions
1
Biomarkers
1
Specialists
0
Symptoms
156
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.