Substance / Medication

Clonidine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

156 trials linked to this intervention

156
Total Trials
17
Recruiting
59
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Development and validation of a paediatric oral formulation of clonidine hydrochloride.
de Goede A L, Boedhram R R, Eckhardt M et al. · Int J Pharm · 2012
PMID: 22580108Observational
Sedation and plasma concentration of clonidine hydrochloride for pre-anesthetic medication in pediatric surgery.
Sumiya Kenji, Homma Masato, Watanabe Machiko et al. · Biol Pharm Bull · 2003
PMID: 12673018Observational
Successful treatment of ptyalism gravidarum with clonidine hydrochloride: A case report.
De Braga Victoria, Dahdouh Elias M, Balayla Jacques · Case Rep Womens Health · 2022
PMID: 35433281Case ReportFull text (PMC)
[A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride].
Shimmura Mitsunori, Kawamura Nobutoshi, Tateishi Takahisa et al. · Rinsho Shinkeigaku · 2016
PMID: 26754594Case Report
Pre-formulation and Stability Study of 20-mcg Clonidine Hydrochloride Pediatric Capsules.
Wasilewski Maya, Curti Christophe, Panuccio Camille et al. · J Pediatr Pharmacol Ther · 2022
PMID: 36186250OtherFull text (PMC)
Stability evaluation of compounded clonidine hydrochloride oral liquids based on a solid-phase extraction HPLC-UV method.
Coache Daphné, Friciu Mihaela, Roullin V Gaëlle et al. · PLoS One · 2021
PMID: 34847160OtherFull text (PMC)
Preparation andevaluation of a clonidine hydrochloride drug-resin suspension as a sustained-release formulation.
Liu Hongfei, Xie Xiaoya, Chen Chao et al. · Drug Dev Ind Pharm · 2021
PMID: 33615926Preclinical
Effect of Clonidine Hydrochloride on Isolated Newborn Rat Heart.
Zefirov T L, Ziyatdinova N I, Kuptsova A M et al. · Bull Exp Biol Med · 2021
PMID: 34855077Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clonidine hydrochloride (substance)
SNOMED CT
387121001
UMLS CUI
C0546860

Clinical Data

This intervention maps to 12 entities in the Healos knowledge graph.

9
Conditions
1
Biomarkers
1
Specialists
0
Symptoms
156
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.