Substance / Medication

Colesevelam hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

921 trials linked to this intervention

921
Total Trials
103
Recruiting
292
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The effect of colesevelam hydrochloride on insulin sensitivity and secretion in patients with type 2 diabetes: a pilot study.
Schwartz Sherwyn L, Lai Yu-Ling, Xu Jianbo et al. · Metab Syndr Relat Disord · 2010
PMID: 20059361RCT
Effects of colesevelam hydrochloride (WelChol) on biomarkers of inflammation in patients with mild hypercholesterolemia.
Devaraj Sridevi, Autret Bryce, Jialal Ishwarlal · Am J Cardiol · 2006
PMID: 16923452RCT
Comparative evaluation of in vitro efficacy of colesevelam hydrochloride tablets.
Krishnaiah Yellela S R, Yang Yongsheng, Bykadi Srikant et al. · Drug Dev Ind Pharm · 2014
PMID: 23805883Observational
Effect of colesevelam hydrochloride on glycemia and insulin sensitivity in men with the metabolic syndrome.
Vega Gloria Lena, Dunn Fredrick L, Grundy Scott M · Am J Cardiol · 2011
PMID: 21813109Observational
Colesevelam hydrochloride: efficacy and safety in pediatric subjects with heterozygous familial hypercholesterolemia.
Stein Evan A, Marais A David, Szamosi Tamas et al. · J Pediatr · 2010
PMID: 19879596Observational
Colesevelam hydrochloride therapy in patients with type 2 diabetes mellitus treated with metformin: glucose and lipid effects.
Bays Harold E, Goldberg Ronald B, Truitt Kenneth E et al. · Arch Intern Med · 2008
PMID: 18852398Observational
Lipoprotein effects of combined ezetimibe and colesevelam hydrochloride versus ezetimibe alone in hypercholesterolemic subjects: a pilot study.
Knopp Robert H, Tsunehara Christine, Retzlaff Barbara M et al. · Metabolism · 2006
PMID: 17142146Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Colesevelam hydrochloride (substance)
SNOMED CT
127965004
UMLS CUI
C0541154

Clinical Data

This intervention maps to 14 entities in the Healos knowledge graph.

5
Conditions
4
Biomarkers
3
Specialists
0
Symptoms
921
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Colesevelam hydrochloride — Conditions, Biomarkers & Specialists | Healos | Healos