Substance / Medication

Cyclophosphamide monohydrate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

19 trials linked to this intervention

19
Total Trials
14
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Chimeric antigen receptor T-cell therapy in adults with B-cell acute lymphoblastic leukemia.
Grover Punita, Veilleux Olivier, Tian Lu et al. · Blood Adv · 2022
PMID: 34610109Meta-AnalysisFull text (PMC)
Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Yide, Meehan Michael T, Burrows Scott R et al. · J Cancer Res Clin Oncol · 2022
PMID: 34705104Meta-AnalysisFull text (PMC)
Chemotherapy Treatments for Burkitt Lymphoma: Systematic Review of Interventional Studies.
Della Rocca Ana M, Leonart Letícia P, Ferreira Vinicius L et al. · Clin Lymphoma Myeloma Leuk · 2021
PMID: 33947633Meta-Analysis
Malaria Infection and Risk for Endemic Burkitt Lymphoma: A Systematic Review and Meta-Analysis.
Kotepui Kwuntida Uthaisar, Kotepui Manas · Int J Environ Res Public Health · 2021
PMID: 34070881Meta-AnalysisFull text (PMC)
A QbD approach for optimizing the lyophilization parameters of cyclophosphamide monohydrate.
Ahammad Shaik Riyaz, Narayanasamy Damodharan · Drug Dev Ind Pharm · 2025
PMID: 40167576Other
Development of a Stable Lyophilized Cyclophosphamide Monohydrate Formulation Using Non-Aqueous Solvents.
Ahammad Shaik Riyaz, Narayanasamy Damodharan · AAPS PharmSciTech · 2024
PMID: 39198332Other
Crystallization of Cyclophosphamide Monohydrate During Lyophilization.
Munjal Bhushan, Zode Sandeep S, Bansal Arvind K · J Pharm Sci · 2019
PMID: 30352215Other
Evaluation of the repeated dose liver micronucleus assay using young adult rats with cyclophosphamide monohydrate: a report of a collaborative study by CSGMT/JEMS.MMS.
Matsumoto Kazumi, Zaizen Kazuyo, Miyamoto Atsushi et al. · Mutat Res Genet Toxicol Environ Mutagen · 2015
PMID: 26065310Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cyclophosphamide monohydrate (substance)
SNOMED CT
725850006
UMLS CUI
C0887682

Clinical Data

This intervention maps to 18 entities in the Healos knowledge graph.

13
Conditions
3
Biomarkers
1
Specialists
0
Symptoms
19
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.