Substance / Medication

Dantrolene sodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Clozapine as a treatment for catatonia: A systematic review.
Saini Aman, Begum Nazifa, Matti James et al. · Schizophr Res · 2024
PMID: 36117082Meta-Analysis
Antipsychotics for schizophrenia spectrum disorders with catatonic symptoms.
Huang Michael W, Gibson Roger Carl, Jayaram Mahesh B et al. · Cochrane Database Syst Rev · 2022
PMID: 35844143Meta-AnalysisFull text (PMC)
A systematic review and pooled, patient-level analysis of predictors of mortality in neuroleptic malignant syndrome.
Guinart Daniel, Misawa Fuminari, Rubio Jose M et al. · Acta Psychiatr Scand · 2021
PMID: 34358327Meta-Analysis
Neuroleptic malignant syndrome in patients with cancer: a systematic review.
Sato Izumi, Onishi Hideki, Kawanishi Chiaki et al. · BMJ Support Palliat Care · 2020
PMID: 32414787Meta-Analysis
HyperCKemia and rhabdomyolysis in the neuroleptic malignant and serotonin syndromes: A literature review.
Kruijt N, van den Bersselaar L R, Wijma J et al. · Neuromuscul Disord · 2020
PMID: 33250373Meta-Analysis
A systematic review of sex and age factors in neuroleptic malignant syndrome diagnosis frequency.
Gurrera Ronald J · Acta Psychiatr Scand · 2017
PMID: 28144982Meta-Analysis
Conundrums in neurology: diagnosing serotonin syndrome - a meta-analysis of cases.
Werneke Ursula, Jamshidi Fariba, Taylor David M et al. · BMC Neurol · 2016
PMID: 27406219Meta-AnalysisFull text (PMC)
[The Neuroleptic Malignant Syndrome].
Nagel M, Freisberg S, Junghanns K et al. · Fortschr Neurol Psychiatr · 2015
PMID: 26200042Meta-Analysis
A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome.
Abreu Damien, Stone Stephen I, Pearson Toni S et al. · JCI Insight · 2021
PMID: 34185708TrialFull text (PMC)
The efficacy of dantrolene sodium in controlling exertional rhabdomyolysis in the Thoroughbred racehorse.
Edwards J G T, Newtont J R, Ramzan P H L et al. · Equine Vet J · 2003
PMID: 14649364Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Dantrolene sodium (substance)
SNOMED CT
81946009
UMLS CUI
C0010977

Clinical Data

This intervention maps to 11 entities in the Ltrl knowledge graph.

6
Conditions
3
Biomarkers
1
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.