Substance / Medication

Desoxycorticosterone pivalate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Development of mass spectrometric methods for determination of desoxycorticosterone pivalate and its esterase product in canine serum.
Lehner A F, Zyskowski Justin, Buchweitz J P et al. · Toxicol Mech Methods · 2025
PMID: 40226906Preclinical
Urine electrolytes do not predict desoxycorticosterone pivalate efficacy in dogs with hypoadrenocorticism.
Langlois Daniel K, Dropkin Casey A, Kruger John M · Am J Vet Res · 2023
PMID: 37279885Preclinical
Clinical features and long-term management of cats with primary hypoadrenocorticism using desoxycorticosterone pivalate and prednisolone.
Sieber-Ruckstuhl Nadja S, Harburger Livia, Hofer Natalie et al. · J Vet Intern Med · 2023
PMID: 36809682PreclinicalFull text (PMC)
Low-dose desoxycorticosterone pivalate treatment of hypoadrenocorticism in dogs: A randomized controlled clinical trial.
Vincent Alysha M, Okonkowski Linda K, Brudvig Jean M et al. · J Vet Intern Med · 2021
PMID: 34114259PreclinicalFull text (PMC)
[Therapy of primary hypoadrenocorticism in dogs with low dose desoxycorticosterone pivalate].
Münch Ludwig, Münch Maria, Paul Helene et al. · Tierarztl Prax Ausg K Kleintiere Heimtiere · 2020
PMID: 32557492Preclinical
Evaluation of a low-dose desoxycorticosterone pivalate treatment protocol for long-term management of dogs with primary hypoadrenocorticism.
Sieber-Ruckstuhl Nadia S, Reusch Claudia E, Hofer-Inteeworn Nathalie et al. · J Vet Intern Med · 2019
PMID: 30865322PreclinicalFull text (PMC)
Desoxycorticosterone pivalate-salt treatment leads to non-dipping hypertension in Per1 knockout mice.
Solocinski K, Holzworth M, Wen X et al. · Acta Physiol (Oxf) · 2017
PMID: 27636900PreclinicalFull text (PMC)
Lower initial dose desoxycorticosterone pivalate for treatment of canine primary hypoadrenocorticism.
Bates J A, Shott S, Schall W D · Aust Vet J · 2013
PMID: 23438457Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Desoxycortone pivalate (substance)
SNOMED CT
116630009
UMLS CUI
C0057420

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.