No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis

NCT05398679Phase 4Recruiting360 enrolled

Oral-only Antibiotics for Bone and Joint Infections in Children

NCT04563325Phase 4Completed180 enrolled

View all 2 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Dicloxacillin is an inducer of intestinal P-glycoprotein but neither dicloxacillin nor flucloxacillin increases the risk of stroke/systemic embolism in direct oral anticoagulant users.

Iversen Ditte B, Dunvald Ann-Cathrine Dalgård, Ernst Martin Thomsen et al. · Br J Clin Pharmacol · 2024

PMID: 39160000RCTFull text (PMC)

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro.

Stage Tore Bjerregaard, Graff Magnus, Wong Susan et al. · Br J Clin Pharmacol · 2018

PMID: 29105855RCTFull text (PMC)

Safety and pharmacokinetics of dicloxacillin in healthy Chinese volunteers following single and multiple oral doses.

Wu Guolan, Zheng Yunliang, Zhou Huili et al. · Drug Des Devel Ther · 2015

PMID: 26527863RCTFull text (PMC)

Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis.

Beringer Paul M, Kriengkauykiat Jane, Zhang Xiyun et al. · Pharmacotherapy · 2008

PMID: 18576903RCT

Ischemic Stroke and Systemic Embolism in Warfarin Users With Atrial Fibrillation or Heart Valve Replacement Exposed to Dicloxacillin or Flucloxacillin.

Hellfritzsch Maja, Lund Lars Christian, Ennis Zandra et al. · Clin Pharmacol Ther · 2020

PMID: 31563140Observational

Bioanalytical method development and validation for simultaneous estimation of cefixime and dicloxacillin by RP-HPLC in human plasma.

Bhinge Somnath D, Malipatil Sharangouda M, Sonawane Lalit V · Acta Chim Slov · 2014

PMID: 25286213Observational

Relative efficacy of cefuroxime versus dicloxacillin as definitive antimicrobial therapy in methicillin-susceptible Staphylococcus aureus bacteraemia: a propensity-score adjusted retrospective cohort study.

Rasmussen Jon Bjarke, Knudsen Jenny Dahl, Arpi Magnus et al. · J Antimicrob Chemother · 2014

PMID: 24078468Observational

Effectiveness of penicillin, dicloxacillin and cefuroxime for penicillin-susceptible Staphylococcus aureus bacteraemia: a retrospective, propensity-score-adjusted case-control and cohort analysis.

Nissen Jette Lindbjerg, Skov Robert, Knudsen Jenny Dahl et al. · J Antimicrob Chemother · 2013

PMID: 23599360Observational

Spectrophotometric determination of flucloxacillin and dicloxacillin in pure and dosage forms.

El-Dien F A Nour, Mohamed Gehad G, Farag Eman Y Z A · Spectrochim Acta A Mol Biomol Spectrosc · 2006

PMID: 16431153Observational

Antibiotic concentrations in serum and wound fluid after local gentamicin or intravenous dicloxacillin prophylaxis in cardiac surgery.

Friberg Orjan, Jones Ian, Sjöberg Lennart et al. · Scand J Infect Dis · 2003

PMID: 12839154Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Dicloxacillin (substance)
SNOMED CT: 372873001
UMLS CUI: C0012093
RxNorm CUI: 3356

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.