No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

13 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Recurrent Throat Infections and Tonsillectomy

NCT00547391Phase 4Completed87 enrolled

Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat

NCT00643539Phase 4Completed360 enrolled

Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy

NCT00654511Phase 4Completed101 enrolled

Efficacy of Tinoridine in Treating Pain and Inflammation in Adults

NCT01224756Phase 4Completed342 enrolled

A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy

NCT01267136Phase 4Completed84 enrolled

View all 13 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Efficacy of oral levofloxacin and dirithromycin alone and in combination with rifampicin in the treatment of experimental murine Brucella abortus infection.

Arda Bilgin, Tunçel Mürşide, Yaimazhan Tansu et al. · Int J Antimicrob Agents · 2004

PMID: 15013048Observational

Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines, and quinolones.

Kenny G E, Cartwright F D · Antimicrob Agents Chemother · 2001

PMID: 11502536ObservationalFull text (PMC)

Comparative Computational Analysis of Dirithromycin and Azithromycin in Search for a Potent Drug against COVID-19 caused by SARS-CoV-2: Evidence from molecular docking and dynamic simulation.

Adel Kadri, Amor Mosbah, Alaeddine Redissi et al. · Cell Mol Biol (Noisy-le-grand) · 2022

PMID: 35818230Other

Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the70S ribosome.

Pichkur Evgeny B, Paleskava Alena, Tereshchenkov Andrey G et al. · RNA · 2020

PMID: 32144191OtherFull text (PMC)

Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides.

Khabibullina Nelli F, Tereshchenkov Andrey G, Komarova Ekaterina S et al. · Antimicrob Agents Chemother · 2019

PMID: 30936109OtherFull text (PMC)

Ocular Application of Dirithromycin Incorporated Polymeric Nanoparticles: anEvaluation.

Başaran Ebru · Turk J Pharm Sci · 2017

PMID: 32454613OtherFull text (PMC)

Evaluation of Possible Genotoxic Activity of Dirithromycin in Cultured Human Lymphocytes.

Kayraldız Ahmet, Dönbak Lale, Yavuz Kocaman Ayşe et al. · J Toxicol · 2015

PMID: 26576152OtherFull text (PMC)

Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin.

Liang Zuozhong, Wang Yuan, Wang Wei et al. · Langmuir · 2015

PMID: 26632998Other

Quantitative determination of erythromycylamine in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study of dirithromycin.

Liu Yun-Qing, Chen Qi-Yuan, Chen Ben-Mei et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2008

PMID: 18296129Other

Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect.

Cai Hua-Lin, Wang Feng, Li Huan-De et al. · J Chromatogr B Analyt Technol Biomed Life Sci · 2014

PMID: 24424301Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Dirithromycin (substance)
SNOMED CT: 96035007
UMLS CUI: C0058445
RxNorm CUI: 23437

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.