Substance / Medication

Donepezil hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
A systematic review of the efficacy of donepezil hydrochloride combined with nimodipine on treating vascular dementia.
Yang Qiang, Liu Jia, Huang Kai-Lin et al. · Medicine (Baltimore) · 2022
PMID: 35945739Meta-AnalysisFull text (PMC)
The effect of donepezil hydrochloride on post-COVID memory impairment: A randomized controlled trial.
Pooladgar Parham, Sakhabakhsh Mehdi, Soleiman-Meigooni Saeed et al. · J Clin Neurosci · 2023
PMID: 37952347RCT
Pilot randomized trial of donepezil hydrochloride for delirium after hip fracture.
Marcantonio Edward R, Palihnich Kerry, Appleton Paul et al. · J Am Geriatr Soc · 2011
PMID: 22091574RCTFull text (PMC)
Role of Omega-3 Fatty Acids and Butter Oil in Targeting Delivery of Donepezil Hydrochloride Microemulsion to Brain via the Intranasal Route: a Comparative Study.
Khunt Dignesh, Shrivas Meenakshee, Polaka Suryanarayana et al. · AAPS PharmSciTech · 2020
PMID: 31900652Observational
Preparation, characterization, and in vivo pharmacokinetics of thermosensitive in situ nasal gel of donepezil hydrochloride.
Gu Fugen, Fan Huimin, Cong Zhixin et al. · Acta Pharm · 2020
PMID: 32074067Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Donepezil hydrochloride (substance)
SNOMED CT
386856007
UMLS CUI
C0771848

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.