Substance / Medication

Doxercalciferol

Overview

Active Ingredient
doxercalciferol
RxNorm CUI
11516

Indications

Doxercalciferol injection is indicated for the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) on dialysis.

Labeler: Eugia US LLCUpdated: 2025-10-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Doxercalciferol is contraindicated in patients with: Warnings and Precautions (5.1) [see] Hypercalcemia Warnings and Precautions (5.1) [see] Vitamin D toxicity Warnings and Precautions (5.3) Adverse Reactions (6.2) [see,]. Known hypersensitivity to doxercalciferol or any of the inactive ingredients

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

11 trials linked to this intervention

11
Total Trials
1
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The prevalence and anatomy of parathyroid glands: a meta-analysis with implications for parathyroid surgery.
Taterra Dominik, Wong Linda M, Vikse Jens et al. · Langenbecks Arch Surg · 2019
PMID: 30762091Meta-AnalysisFull text (PMC)
Efficacy and safety of paricalcitol in patients undergoing hemodialysis: a meta-analysis.
Liu Yang, Liu Ling-Yun, Jia Ye et al. · Drug Des Devel Ther · 2019
PMID: 30992658Meta-AnalysisFull text (PMC)
Phase II study of doxercalciferol for the treatment of myelodysplastic syndrome.
Petrich Adam, Kahl Brad, Bailey Howard et al. · Leuk Lymphoma · 2008
PMID: 18203012TrialFull text (PMC)
Intermittent doxercalciferol (1alpha-hydroxyvitamin D(2)) therapy for secondary hyperparathyroidism.
Frazão J M, Elangovan L, Maung H M et al. · Am J Kidney Dis · 2000
PMID: 10977787Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Doxercalciferol (substance)
SNOMED CT
116094003
UMLS CUI
C0043668
RxNorm CUI
11516
Labeler
Eugia US LLC

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
11
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.