Substance / Medication

Doxycycline hyclate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

22 trials linked to this intervention

22
Total Trials
1
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Pharmacokinetics of an oral extended-release formulation of doxycycline hyclate containing acrylic acid and polymethacrylate in dogs.
Ruiz Sara Melisa Arciniegas, Olvera Lilia Gutiérrez, Chacón Sara del Carmen Caballero et al. · Am J Vet Res · 2015
PMID: 25815578RCT
Experimental determination of a subantimicrobial dosage of doxycycline hyclate for treatment of periodontitis in Beagles.
Kim Se Eun, Kim Soohee, Jeong Manbok et al. · Am J Vet Res · 2013
PMID: 23270357RCT
Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis.
Vijayabala G Sree, Kalappanavar Anupama N, Annigeri Rajeshwari G et al. · Oral Surg Oral Med Oral Pathol Oral Radiol · 2013
PMID: 24035110RCT
Comparative evaluation of the efficacy of 10% doxycycline hyclate in the periodontal treatment of smokers - a clinical and microbiological study.
Sandhya Y P, Prabhuji M L, Chandra Rampalli Viswa · Oral Health Prev Dent · 2011
PMID: 21594208RCT
Pharmacokinetics of an injectable long-acting parenteral formulation of doxycycline hyclate in pigs.
Gutiérrez L, Ocampo L, Espinosa F et al. · J Vet Pharmacol Ther · 2014
PMID: 23866042Trial
Pharmacokinetics of a peroral single dose of two long-acting formulations and an aqueous formulation of doxycycline hyclate in horses.
Zozaya Heidi, Gutierrez Lilia, Bernad Maria Josefa et al. · Acta Vet Scand · 2013
PMID: 23497696TrialFull text (PMC)
Effect of locally delivered doxycycline hyclate on human fibroblast attachment to subgingival calculus.
Sayed-Suleyman Amer, Yukna Raymond A, Vastardis Sotirios et al. · J Periodontol · 2005
PMID: 15974845Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Doxycycline hyclate (substance)
SNOMED CT
71417000
UMLS CUI
C0058731

Clinical Data

This intervention maps to 12 entities in the Ltrl knowledge graph.

12
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
22
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.