Substance / Medication

Echothiophate

Overview

Active Ingredient
ecothiopate
RxNorm CUI
89778

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

136 trials linked to this intervention

136
Total Trials
11
Recruiting
53
With Results

Research Evidence

Published studies and systematic reviews

Sort:
PreserFlo MicroShunt versus trabeculectomy: an updated meta-analysis and systematic review.
Governatori Lorenzo, Oliverio Leandro, Mermoud André et al. · Graefes Arch Clin Exp Ophthalmol · 2025
PMID: 39394492Meta-Analysis
GLP-1 Receptor Agonists Use and Incidence of Glaucoma: A Systematic Review and Meta-Analysis.
Amaral Dillan Cunha, Guedes Jaime, Cruz Matheus Ribeiro Barbosa et al. · Am J Ophthalmol · 2025
PMID: 39732312Meta-Analysis
Machine Learning Approaches in High Myopia: Systematic Review and Meta-Analysis.
Zuo Huiyi, Huang Baoyu, He Jian et al. · J Med Internet Res · 2025
PMID: 39753217Meta-AnalysisFull text (PMC)
Association between gene polymorphisms and glaucoma susceptibility among Africans: a systematic review and meta-analysis.
Asiamah Randy, Kyei Samuel, Owusu Paul et al. · Ophthalmic Genet · 2025
PMID: 39757584Meta-Analysis
Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate.
Pittel Zipora, Barak Dov, Segall Yoffi · Brain Res · 2006
PMID: 16580648Observational
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Nachon Florian, Asojo Oluwatoyin A, Borgstahl Gloria E O et al. · Biochemistry · 2005
PMID: 15667209Observational
Intraocular pressure control with echothiophate iodide in children's eyes with glaucoma after cataract extraction.
Kraus Courtney L, Trivedi Rupal H, Wilson M Edward · J AAPOS · 2015
PMID: 25818282Other
Lowering of IOP by echothiophate iodide in pseudophakic eyes with glaucoma.
Schmidt K G, Horowitz Yosefa, Buckman Gila et al. · Curr Eye Res · 2010
PMID: 20673046Other
H-7 effect on outflow facility after trabecular obstruction following long-term echothiophate treatment in monkeys.
Gabelt B'Ann T, Hennes Elizabeth A, Seeman Jennifer L et al. · Invest Ophthalmol Vis Sci · 2004
PMID: 15277498Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ecothiopate (substance)
SNOMED CT
387339003
UMLS CUI
C0301366
RxNorm CUI
89778

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

2
Conditions
1
Biomarkers
1
Specialists
0
Symptoms
136
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.