Substance / Medication

Ephedrine sulfate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Orthostatic hypotension

Rhinitis

Airway hyperreactivity

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Leukocytes

LOINC 26464-8

secondary

Eosinophils

LOINC 711-2

primary

IgE

LOINC 19113-0

primary

Clinical Trials

359 trials linked to this intervention

359

Total Trials

Recruiting

119

With Results

Recent Trials

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

NCT00001406Recruiting800 enrolled

Role of Genetic Factors in the Development of Lung Disease

NCT00001532Recruiting3500 enrolled

Sample Collections From the Airways of Asthmatic Patients

NCT00001888Completed574 enrolled

A Study for Patients With Neurogenic Orthostatic Hypotension

NCT00046475Phase 4Completed140 enrolled

Nasonex Compared With Placebo in Participants With Seasonal Allergic Rhinitis (SAR) and Concomitant Asthma (P03280)

NCT00070707Phase 4Completed188 enrolled

View all 359 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Treatment of severe snoring with a combination of pseudoephedrine sulfate and domperidone.

Larrain Augusto, Hudson Monica, Dominitz Jason A et al. · J Clin Sleep Med · 2006

PMID: 17557432RCT

Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.

Mizoguchi H, Wilson A, Jerdack G R et al. · Int J Clin Pharmacol Ther · 2007

PMID: 17474541Observational

A new HPLC approach for the determination of hydrophilic and hydrophobic components: the case of pseudoephedrine sulfate and loratadine in tablets.

Abu-Lathou Ali, Hamdan Imad I, Tahraoui Ahmed · Drug Dev Ind Pharm · 2005

PMID: 16109631Observational

Use of Intramuscular Ephedrine Sulfate During Kidney Transplantation.

Patel Gaurav P, Smith Susan A, Romej Michelle et al. · Clin Pharmacol · 2023

PMID: 37387793Case ReportFull text (PMC)

Determination of loratadine and pseudoephedrine sulfate in pharmaceuticals based on non-linear second-order spectrophotometric data generated by a pH-gradient flow injection technique and artificial neural networks.

Culzoni María J, Goicoechea Héctor C · Anal Bioanal Chem · 2007

PMID: 17955218Other

Simultaneous determination of loratadine and pseudoephedrine sulfate in human plasma by liquid chromatography-electrospray mass spectrometry for pharmacokinetic studies.

Sun Jianguo, Wang Guangji, Wang Wei et al. · J Pharm Biomed Anal · 2005

PMID: 15953705Other

Development of modified-release dosage forms containing loratadine and pseudoephedrine sulfate.

Sznitowska Małgorzata, Cal Krzysztof, Kupiec Katarzyna · Acta Pol Pharm · 2004

PMID: 15909946Other

Simultaneous determination of loratadine and pseudoephedrine sulfate in pharmaceutical formulation by RP-LC and derivative spectrophotometry.

Mabrouk M M, el-Fatatry H M, Hammad Sherin et al. · J Pharm Biomed Anal · 2003

PMID: 14623585Other

Quantitative and structural determination of pseudoephedrine sulfate and its related compounds in pharmaceutical preparations using high-performance liquid chromatography.

Wu Nian, Feng Wenqing, Lin Elizabeth et al. · J Pharm Biomed Anal · 2002

PMID: 12408905Other

A comparative study of the side effects between pseudoephedrine in Loratadine plus Pseudoephedrine Sulfate Repetabs Tables and loratadine + pseudoephedrine tablet in treatment of allergic rhinitis in Thai patients.

Supiyaphun Pakpoom, Chochaipanichnon Ladda, Kerekhanjanarong Virachai et al. · J Med Assoc Thai · 2002

PMID: 12322847Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Allergy & Immunology (Internal Medicine) Physician

Internal Medicine — Allergy & Immunology

NUCC 207RA0201X

Pulmonary Disease Physician

Internal Medicine — Pulmonary Disease

NUCC 207RP1001X

Find a Provider

Health Goals

Goals connected through associated conditions

Support Respiratory Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Ephedrine sulfate (substance)
SNOMED CT: 76525000
UMLS CUI: C0304426

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

359

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.