Substance / Medication

Ethacrynic acid

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

12 trials linked to this intervention

12
Total Trials
2
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of the cat deafening method: Co-administration of ethacrynic acid and kanamycin.
Jang Jeong Hun, Lee Ho Sun, Oh Seung Ha et al. · Acta Otolaryngol · 2016
PMID: 26605909Observational
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
Ricci Zaccaria, Haiberger Roberta, Pezzella Chiara et al. · Crit Care · 2015
PMID: 25563826ObservationalFull text (PMC)
Effects of novel ethacrynic acid derivatives on human trabecular meshwork cell shape, actin cytoskeletal organization, and transcellular fluid flow.
Rao Ponugoti Vasantha, Shimazaki Atsushi, Ichikawa Masaki et al. · Biol Pharm Bull · 2005
PMID: 16327147Observational
Novel antiglaucoma prodrugs and codrugs of ethacrynic acid.
Cynkowska Grazyna, Cynkowski Tadeusz, Al-Ghananeem Abeer M et al. · Bioorg Med Chem Lett · 2005
PMID: 15990301Observational
Effects of the new ethacrynic acid derivative SA9000 on intraocular pressure in cats and monkeys.
Shimazaki Atsushi, Ichikawa Masaki, Rao Ponugoti Vasantha et al. · Biol Pharm Bull · 2004
PMID: 15256733Observational
Differential response of bipolar and normal control lymphoblastoid cell sodium pump to ethacrynic acid.
Li Rena, El-Mallakh Rif S · J Affect Disord · 2004
PMID: 15094253Observational
Ethacrynic acid as potential drug for diuretic renography in instance of sulfonamide allergy.
Nguyen Ba D, Roarke Michael C, Howard Osborn H · Clin Nucl Med · 2010
PMID: 20548157Case Report
Ethacrynic acid can be effective for refractory congestive heart failure and ascites.
Alisky Joseph M, Tuttle Thomas F · South Med J · 2003
PMID: 14632366Case Report
Ethacrynic acid and the sulfa-sensitive patient.
Wall Geoffrey C, Bigner Dori, Craig Steven · Arch Intern Med · 2003
PMID: 12523926Case Report
Discovery of repurposed ethacrynic acid and its derivatives as novel TEAD inhibitors.
Chen Wei, Nan Yuqing, Zhang Yiping et al. · Eur J Med Chem · 2026
PMID: 41161055Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Etacrynic acid (substance)
SNOMED CT
373536004
UMLS CUI
C0014963

Clinical Data

This intervention maps to 16 entities in the Healos knowledge graph.

9
Conditions
4
Biomarkers
2
Specialists
0
Symptoms
12
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.