Substance / Medication

Ethambutol

Overview

Active Ingredient
ethambutol
RxNorm CUI
4110

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Ethambutol optic neuropathy in the extended anti-tubercular therapy regime: A systematic review.
Sabhapandit Swapnali, Gella Vishwanath, Shireesha Anumula et al. · Indian J Ophthalmol · 2023
PMID: 36872667Meta-AnalysisFull text (PMC)
Diagnosis of Drug Resistance to Fluoroquinolones, Amikacin, Capreomycin, Kanamycin and Ethambutol with Genotype MTBDRsl Assay: a Meta-Analysis.
Mao Xiaolu, Ke Zunqiong, Shi Xiaoyan et al. · Ann Clin Lab Sci · 2015
PMID: 26586705Meta-Analysis
Incidence of ethambutol-related visual impairment during treatment of active tuberculosis.
Ezer N, Benedetti A, Darvish-Zargar M et al. · Int J Tuberc Lung Dis · 2013
PMID: 23394767Meta-Analysis
Pharmacokinetics of ethambutol and weight banded dosing in South African adults newly diagnosed with tuberculosis and HIV.
Ndzamba Bonginkosi, Denti Paolo, McIlleron Helen et al. · Antimicrob Agents Chemother · 2025
PMID: 39714183RCTFull text (PMC)
Lower dose of ethambutol may reduce ocular toxicity without radiological deterioration for Mycobacterium avium complex pulmonary disease.
Ando Takahiro, Kage Hidenori, Matsumoto Yoko et al. · Respir Investig · 2021
PMID: 34389250RCT
Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Newly Diagnosed Pulmonary TB Patients in Tanzania.
Denti Paolo, Jeremiah Kidola, Chigutsa Emmanuel et al. · PLoS One · 2015
PMID: 26501782RCTFull text (PMC)
Efficacy of clarithromycin and ethambutol for Mycobacterium avium complex pulmonary disease. A preliminary study.
Miwa Seiichi, Shirai Masahiro, Toyoshima Mikio et al. · Ann Am Thorac Soc · 2014
PMID: 24298907RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ethambutol (substance)
SNOMED CT
387129004
UMLS CUI
C0014964
RxNorm CUI
4110

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.