Substance / Medication

Faricimab

Overview

Active Ingredient
faricimab
RxNorm CUI
2591519

Indications

VABYSMO is a vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang-2) inhibitor indicated for the treatment of patients with:

Labeler: Genentech, Inc.Updated: 2026-01-20T00:00:00.000ZFull label on DailyMed

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

7 trials linked to this intervention

7
Total Trials
6
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Budget Impact of Faricimab in Neovascular Age-Related Macular Degeneration in the Netherlands: A Systematic Review and Meta-Analysis of Injection Count.
El Alili Mohamed, van de Laar Celine J, de Greeff Jeroen P F et al. · Ophthalmol Ther · 2026
PMID: 41543675Meta-Analysis
Efficacy of Faricimab in Neovascular Age-Related Macular Degeneration: A Single-Arm Systematic Review and Meta-Analysis.
Karam Mohammad, Baeshen Moath, Alfuzaie Rashed et al. · Ophthalmic Res · 2026
PMID: 41499325Meta-Analysis
Efficacy of intravitreal faricimab therapy for polypoidal choroidal vasculopathy: A systematic review and meta-analysis.
Arnold-Vangsted Andreas, Schou Marianne G, Balaratnasingam Chandrakumar et al. · Acta Ophthalmol · 2025
PMID: 39548881Meta-Analysis
Switching to faricimab after prior anti-vascular endothelial growth factor therapy for persistent diabetic macular edema: a systematic review and meta-analysis.
Tahmasebi Ali, Ebrahimiadib Nazanin, Niyousha Mohammadreza et al. · Graefes Arch Clin Exp Ophthalmol · 2025
PMID: 40571775Meta-Analysis
Clinical Efficacy of Switching to Faricimab in Treatment Resistant Neovascular Age-Related Macular Degeneration: Systematic Review and Meta-analysis.
Zhang Charles, Aboukasm Georges, Lai Daniel A et al. · Am J Ophthalmol · 2025
PMID: 40849032Meta-Analysis
Efficacy and safety of faricimab for neovascular age-related macular degeneration: a systematic review and network meta-analysis.
Samacá-Samacá Daniel, Hernández-Castillo Claudia, Prieto-Pinto Laura et al. · BMJ Open Ophthalmol · 2024
PMID: 39043575Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Faricimab (substance)
SNOMED CT
278201000202106
UMLS CUI
C5139890
RxNorm CUI
2591519
Labeler
Genentech, Inc.

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
7
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.