Substance / Medication

Fenofibrate

Overview

Active Ingredient
fenofibrate
RxNorm CUI
8703
Labeler: PD-Rx Pharmaceuticals, Inc.Updated: 2026-02-26T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Fenofibrate is contraindicated in patients with: [see Clinical Pharmacology (12.3)]. Severe renal impairment, including those with end-stage renal disease (ESRD) and those receiving dialysis [see Warnings and Precautions (5.2)]. Active liver disease, including those with unexplained persistent liver

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

20 trials linked to this intervention

20
Total Trials
0
Recruiting
10
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of fenofibrate in combination with phototherapy for the treatment of neonatal hyperbilirubinemia: a systematic review and meta-analyses.
Abdellatif Mohammed, Abozaid Ali Ahmed Fouad, Shah Prakesh S et al. · Can J Physiol Pharmacol · 2024
PMID: 38011686Meta-Analysis
Fenofibrate for diabetic retinopathy.
Kataoka Sachiko Y, Lois Noemi, Kawano Sumihiro et al. · Cochrane Database Syst Rev · 2023
PMID: 37310870Meta-AnalysisFull text (PMC)
Efficacy of Pemafibrate Versus Fenofibrate Administration on Serum Lipid Levels in Patients with Dyslipidemia: Network Meta-Analysis and Systematic Review.
Khan Muhammad Shayan, Ghumman Ghulam Mujtaba, Baqi Abdul et al. · Am J Cardiovasc Drugs · 2023
PMID: 37524955Meta-Analysis
Impact of fenofibrate therapy on serum uric acid concentrations: a review and meta-analysis.
Zhang Jie, Ji Xiaopeng, Dong Zehua et al. · Endocr J · 2021
PMID: 33731500Meta-Analysis
Pemafibrate Tends to have Better Efficacy in Treating Dyslipidemia than Fenofibrate.
Wang Haizhou, Li Haiou, Zhou Yunjiao et al. · Curr Pharm Des · 2019
PMID: 31769360Meta-Analysis
Effect of fenofibrate on plasma apolipoprotein C-III levels: a systematic review and meta-analysis of randomised placebo-controlled trials.
Sahebkar Amirhossein, Simental-Mendía Luis E, Katsiki Niki et al. · BMJ Open · 2019
PMID: 30798284Meta-AnalysisFull text (PMC)
Effect of micronized fenofibrate on microvascular complications of type 2 diabetes: a systematic review.
Czupryniak Leszek, Joshi Shashank R, Gogtay Jaideep A et al. · Expert Opin Pharmacother · 2016
PMID: 27267786Meta-Analysis
Fenofibrate is effective adjunctive therapy in the treatment of primary biliary cirrhosis: A meta-analysis.
Grigorian Alla Y, Mardini Houssam E, Corpechot Christophe et al. · Clin Res Hepatol Gastroenterol · 2015
PMID: 25882906Meta-Analysis
Plasma uric acid concentrations are reduced by fenofibrate: A systematic review and meta-analysis of randomized placebo-controlled trials.
Derosa Giuseppe, Maffioli Pamela, Sahebkar Amirhossein · Pharmacol Res · 2015
PMID: 26384444Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Fenofibrate (substance)
SNOMED CT
386879008
UMLS CUI
C0033228
RxNorm CUI
8703
Labeler
PD-Rx Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
20
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.