Substance / Medication

Fexofenadine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Urticaria

Nonseasonal allergic rhinitis

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Bioequivalence of 2 Pediatric Formulations of Fexofenadine Hydrochloride Oral Suspension.

Rauch Clemence, Lucio Luiz, De Fer Beatrice Bois et al. · Clin Pharmacol Drug Dev · 2023

PMID: 37655364RCT

A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.

Takahashi Goro, Matsuzaki Zensei, Okamoto Atsushi et al. · Allergol Int · 2012

PMID: 22189593RCT

Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies.

Berkowitz Robert B, McCafferty Frank, Lutz Cheryl et al. · Clin Ther · 2006

PMID: 17157121RCT

The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.

Spector Sheldon L, Shikiar Richard, Harding Gale et al. · Cutis · 2007

PMID: 17388220Observational

Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.

Hampel Frank C, Kittner Barbara, van Bavel Julius H · Ann Allergy Asthma Immunol · 2007

PMID: 18219837Observational

Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.

Breier Ana R, Paim Clésio S, Steppe Martin et al. · J Pharm Pharm Sci · 2005

PMID: 16124939Observational

Formulation and Bioequivalence Evaluation of a Miniaturized Fexofenadine Hydrochloride Tablet.

Song Woo-Yul, Han Chang-Soo, Yu Won-Sang et al. · Pharmaceutics · 2025

PMID: 40574068OtherFull text (PMC)

Eco-friendly synchronous fluorescence spectrofluorimetric method for simultaneous determination of montelukast sodium and fexofenadine hydrochloride in their antiallergic rhinitis fixed-dose combination tablets.

Abdel Hamid Mohamed A, Mabrouk Mokhtar M, Michael Mary A · Luminescence · 2023

PMID: 38098178Other

Application of green first derivative synchronous spectrofluorometric method for quantitative analysis of fexofenadine hydrochloride and pseudoephedrine hydrochloride in pharmaceutical preparation and spiked human plasma.

Ramzy Sherif, Abdelazim Ahmed H, Hasan Mohamed A · BMC Chem · 2022

PMID: 35986381OtherFull text (PMC)

Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In situ and in vivo Investigation.

Sultan Amal A, El Nashar Nourhan F, Ashmawy Shimaa M et al. · Int J Nanomedicine · 2022

PMID: 35983479PreclinicalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Fexofenadine hydrochloride (substance)
SNOMED CT: 108653007
UMLS CUI: C0771752

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.