Substance / Medication

Fexofenadine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Urticaria

Nonseasonal allergic rhinitis

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Evaluation of Pharmacological Treatments for Acute Urticaria: A Systematic Review and Meta-Analysis.

Jamjanya Sirinda, Danpanichkul Pojsakorn, Ongsupankul Sorawit et al. · J Allergy Clin Immunol Pract · 2024

PMID: 38280453Meta-Analysis

Efficacy and Safety of Systemic Corticosteroids for Urticaria: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Chu Xiajing, Wang Jason, Ologundudu Leonardo et al. · J Allergy Clin Immunol Pract · 2024

PMID: 38642709Meta-Analysis

Bioequivalence of 2 Pediatric Formulations of Fexofenadine Hydrochloride Oral Suspension.

Rauch Clemence, Lucio Luiz, De Fer Beatrice Bois et al. · Clin Pharmacol Drug Dev · 2023

PMID: 37655364RCT

A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.

Takahashi Goro, Matsuzaki Zensei, Okamoto Atsushi et al. · Allergol Int · 2012

PMID: 22189593RCT

Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled allergen exposure unit studies.

Berkowitz Robert B, McCafferty Frank, Lutz Cheryl et al. · Clin Ther · 2006

PMID: 17157121RCT

Effect of fexofenadine hydrochloride on cedar pollinosis.

Miyabe Satoshi, Koizuka Izumi, Ochi Kentaro et al. · Auris Nasus Larynx · 2003

PMID: 12543163Trial

A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.

Ridout Fran, Shamsi Ziba, Meadows Robert et al. · Clin Ther · 2003

PMID: 12867226Trial

Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.

Spangler Dennis L, Abelson Mark B, Ober Andrew et al. · Clin Ther · 2003

PMID: 14512132Trial

Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.

Hampel Frank, Ratner Paul, Mansfield Lyndon et al. · Ann Allergy Asthma Immunol · 2003

PMID: 14582814Trial

Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis.

Van Cauwenberge P, Juniper E F · Clin Exp Allergy · 2000

PMID: 10848909Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Fexofenadine hydrochloride (substance)
SNOMED CT: 108653007
UMLS CUI: C0771752

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.