Substance / Medication

Flurbiprofen

Overview

Active Ingredient
flurbiprofen
RxNorm CUI
4502

Indications

Flurbiprofen tablets are indicated: For relief of the signs and symptoms of rheumatoid arthritis. For relief of the signs and symptoms of osteoarthritis.

Labeler: Genus LifesciencesUpdated: 2026-02-03T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Flurbiprofen tablets are contraindicated in the following patients: Warnings and Precautions (5.7 5.9) see, Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to flurbiprofen or any components of the drug product [] Warnings and Precautions (5.7 5.8) see, History of ast

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

45 trials linked to this intervention

45
Total Trials
3
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A systematic review of flurbiprofen 8.75 mg dose and risk of adverse events (excluding haemorrhagic) resulting from drug-drug interactions.
Evans Alison, Roy Debabrata, Dhanda Sandeep et al. · Front Pharmacol · 2024
PMID: 38510649Meta-AnalysisFull text (PMC)
Efficacy of Flurbiprofen for Postoperative Pain in Chinese Surgical Patients: A Meta-Analysis.
Sun Mingyang, Cong Xuhui, Chang Enqiang et al. · J Surg Res · 2020
PMID: 32247074Meta-Analysis
Single dose oral flurbiprofen for acute postoperative pain in adults.
Sultan Asquad, McQuay Henry J, Moore R Andrew et al. · Cochrane Database Syst Rev · 2009
PMID: 19588427Meta-AnalysisFull text (PMC)
Flurbiprofen in the symptomatic management of rheumatoid arthritis: a valuable alternative.
Richy F, Rabenda V, Mawet A et al. · Int J Clin Pract · 2007
PMID: 17596188Meta-Analysis
Comparison of the analgesic efficacy of spray and tablet flurbiprofen for pain after soft tissue surgery.
Eroglu Cennet Neslihan, Yuksek Mehmet Nuri, Elasan Sadi et al. · Braz Oral Res · 2024
PMID: 39536200RCTFull text (PMC)
Flurbiprofen in the subglottic space to prevent postoperative sore throat after cardiac surgery: A randomized double-blind study.
Calabrese Maria, Arlotta Gabriella, Antoniucci Maria Enrica et al. · J Clin Anesth · 2024
PMID: 38430636RCT
A single, maximal dose of celecoxib, ibuprofen, or flurbiprofen does not reduce the muscle signalling response to plyometric exercise in young healthy adults.
Roberts Brandon M, Geddis Alyssa V, Sczuroski Cara E et al. · Eur J Appl Physiol · 2024
PMID: 39044030RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Flurbiprofen (substance)
SNOMED CT
373506008
UMLS CUI
C0016377
RxNorm CUI
4502
Labeler
Genus Lifesciences

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

5
Conditions
2
Biomarkers
1
Specialists
0
Symptoms
45
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.