Substance / Medication

Fluvoxamine maleate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

48 trials linked to this intervention

48
Total Trials
5
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Pharmacokinetics and bioequivalence studies of fluvoxamine maleate tablets in healthy Chinese subjects.
She Ding-Ping, He Ying, Li Ming-Qu et al. · Biomed Chromatogr · 2023
PMID: 36849133RCT
A preliminary study of fluvoxamine maleate on depressive state and serum melatonin levels in patients after cerebral infarction.
Sunami Eiko, Usuda Kazuhiro, Nishiyama Yutaka et al. · Intern Med · 2012
PMID: 22687788RCT
Use of acetylacetone for nano-level assay of fluvoxamine maleate in pure form and pharmaceutical formulation.
Abu-Hassan Ahmed A, Omar Mahmoud A, Derayea Sayed M · Luminescence · 2020
PMID: 32519373Other
Development of sustained release oral disintegrating tablet of fluvoxamine maleate.
Shetaa Esraa A, Arafa Mona F, Abu-Risha Sally E et al. · Pharm Dev Technol · 2025
PMID: 40794462Preclinical
Fluvoxamine maleate alleviates amyloid-beta load and neuroinflammation in 5XFAD mice to ameliorate Alzheimer disease pathology.
Kaur Sukhleen, Sharma Kuhu, Sharma Ankita et al. · Front Immunol · 2024
PMID: 39136022PreclinicalFull text (PMC)
Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory.
Dallé Ernest, Daniels Willie M U, Mabandla Musa V · Brain Res Bull · 2017
PMID: 28549887Preclinical
Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression.
Dallé Ernest, Daniels Willie M U, Mabandla Musa V · Behav Brain Res · 2017
PMID: 27569183Preclinical
Anti-parkinsonian effects of fluvoxamine maleate in maternally separated rats.
Dallé Ernest, Daniels Willie M U, Mabandla Musa V · Int J Dev Neurosci · 2016
PMID: 27338206Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Fluvoxamine maleate (substance)
SNOMED CT
116522003
UMLS CUI
C0700473

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

3
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
48
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.