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Substance / Medication

Fosinopril

SNOMED 372510000 UMLS C0118168

Overview

Active Ingredient

fosinopril

RxNorm CUI

50166

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

High blood pressure

Diabetic renal disease

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

LOINC 2160-0

secondary

LOINC 2823-3

secondary

Natriuretic peptide.B

LOINC 30934-4

primary

Natriuretic peptide.B prohormone N-Terminal

LOINC 33762-6

primary

Clinical Trials

3 trials linked to this intervention

3

Total Trials

1

Recruiting

1

With Results

Recent Trials

Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery

NCT01669434Phase 4Completed291 enrolled

NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients

NCT02817360Phase 4Recruiting2400 enrolled

Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)

NCT01014338Phase 4Completed80 enrolled

View all 3 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Effect of pravastatin and fosinopril on recurrent urinary tract infections.

Pouwels Koen B, Visser Sipke T, Hak Eelko · J Antimicrob Chemother · 2013

PMID: 23111852RCTFull text (PMC)

Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT).

Brouwers Frank P, Asselbergs Folkert W, Hillege Hans L et al. · Am Heart J · 2011

PMID: 21641365RCT

Effects of combination therapy with amlodipine and fosinopril administered at different times on blood pressure and circadian blood pressure pattern in patients with essential hypertension.

Meng Yanyan, Zhang Zixin, Liang Xiaoguang et al. · Acta Cardiol · 2010

PMID: 20666269RCT

[Efficacy of fosinopril on proteinuria in children with Henoch-Schonlein purpura nephritis].

Xu Jian, Cong Hui, Sheng Yu · Zhongguo Dang Dai Er Ke Za Zhi · 2009

PMID: 19292967RCT

[Plasma tissue factor and serum angiotensin II and the therapeutic effect of different dosages of fosinopril on chronic heart failure].

Ma Qilin, Yang Lijie, Yang Tianlun et al. · Zhong Nan Da Xue Xue Bao Yi Xue Ban · 2009

PMID: 19483295RCT

Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria.

van der Harst Pim, Asselbergs Folkert W, Hillege Hans L et al. · Am J Cardiol · 2008

PMID: 18602526RCT

Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects.

Asselbergs Folkert W, van der Harst Pim, van Roon Arie M et al. · Atherosclerosis · 2008

PMID: 17141245RCT

The efficacy and tolerability of fosinopril in Chinese type 2 diabetic patients with moderate renal insufficiency.

Tong P C Y, Ko G T C, Chan W-B et al. · Diabetes Obes Metab · 2006

PMID: 16634995RCT

Racial differences are seen in blood pressure response to fosinopril in hypertensive children.

Menon Sharad, Berezny Katherine Y, Kilaru Rakhi et al. · Am Heart J · 2006

PMID: 16875928RCT

Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

Saber Sameh, Mahmoud Amr A A, Goda Reham et al. · Toxicol Lett · 2018

PMID: 29859236Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Internal Medicine Physician

Internal Medicine

NUCC 207R00000X

Cardiovascular Disease Physician

Internal Medicine — Cardiovascular Disease

NUCC 207RC0000X

Find a Provider

Health Goals

Goals connected through associated conditions

Improve Cardiovascular Fitness

Quick Facts

Type: Substance / Medication
Fully Specified Name: Fosinopril (substance)
SNOMED CT: 372510000
UMLS CUI: C0118168
RxNorm CUI: 50166

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

3

Conditions

4

Biomarkers

2

Specialists

0

Symptoms

3

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.