Substance / Medication

Hexachlorophene

Overview

Active Ingredient
hexachlorophene
RxNorm CUI
5293

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

97 trials linked to this intervention

97
Total Trials
4
Recruiting
64
With Results

Research Evidence

Published studies and systematic reviews

Sort:
KMnO-mediated reactions for hexachlorophene in aqueous solutions: Direct oxidation, self-coupling, and cross-coupling.
Cao Wanming, Yu Yao, Wei Junyan et al. · Chemosphere · 2020
PMID: 32599382Other
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Ambrose Andrew J, Zerio Christopher J, Sivinski Jared et al. · Bioorg Med Chem Lett · 2019
PMID: 31129054OtherFull text (PMC)
Effects of Hexachlorophene, a Chemical Accumulating in Adipose Tissue, on Mouse and Human Mesenchymal Stem Cells.
Leśniak Monika, Zdanowski Robert, Suska Milena et al. · Tissue Eng Regen Med · 2018
PMID: 30603548OtherFull text (PMC)
In vivo mapping of rat brain partial white matter content using hexachlorophene-induced neurotoxicity model.
Liachenko Serguei, Sarkar Sumit · Brain Res · 2024
PMID: 38365131Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Hexachlorophene (substance)
SNOMED CT
387103004
UMLS CUI
C0019435
RxNorm CUI
5293

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
97
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.