Substance / Medication

Human antithrombin III

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Pregnancy-Related Venous Thromboembolism Risk in Asymptomatic Women With Antithrombin Deficiency: A Systematic Review.
Rhéaume Maxime, Weber Florence, Durand Madeleine et al. · Obstet Gynecol · 2016
PMID: 26959206Meta-Analysis
Natural anticoagulants deficiency and the risk of venous thromboembolism: a meta-analysis of observational studies.
Di Minno Matteo Nicola Dario, Ambrosino Pasquale, Ageno Walter et al. · Thromb Res · 2015
PMID: 25784135Meta-Analysis
Antithrombin deficiency after prolonged asparaginase treatment in children with acute lymphoblastic leukemia.
Ranta Susanna, Heyman Mats M, Jahnukainen Kirsi et al. · Blood Coagul Fibrinolysis · 2013
PMID: 24056293RCT
Heparin Resistance - Clinical Perspectives and Management Strategies.
Levy Jerrold H, Connors Jean M · N Engl J Med · 2021
PMID: 34437785Review
Antithrombin Deficiency in Trauma and Surgical Critical Care.
Ehrhardt John D, Boneva Dessy, McKenney Mark et al. · J Surg Res · 2020
PMID: 32799002Review
Laboratory Diagnostics in Thrombophilia.
Linnemann Birgit, Hart Christina · Hamostaseologie · 2019
PMID: 30703819Review
Management of antithrombin deficiency: an update for clinicians.
Bravo-Pérez Carlos, Vicente Vicente, Corral Javier · Expert Rev Hematol · 2019
PMID: 31116611Review
The genetics of antithrombin.
Corral Javier, de la Morena-Barrio María Eugenia, Vicente Vicente · Thromb Res · 2018
PMID: 30005274Review

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Human antithrombin III (substance)
SNOMED CT
412564003
UMLS CUI
C0724532

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.