Substance / Medication

Hyaluronic acid

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Hyaluronic acid and chondroitin sulphate instillation in chronic bladder diseases: a meta-analysis.
Corona Giovanni, Capogrosso Paolo, Baldini Sara et al. · BJU Int · 2026
PMID: 41139434Meta-Analysis
A prisma-based systematic review on the effect of high and low molecular weight hyaluronic acid on IL-1, IL-6, IL-10, CD44, p53, and RHAMM in cellular response related to bone regeneration.
Indrawati Dwi Wahyu, Setiawatie Ernie Maduratna, Rahayu Retno Pudji et al. · Int J Biol Macromol · 2026
PMID: 41344468Meta-Analysis
The Effect of Local Hyaluronic Acid Injection on Skin Aging: A Systematic Review and Meta-Analysis.
Zhou Rongying, Yu Mei · J Cosmet Dermatol · 2025
PMID: 39807700Meta-AnalysisFull text (PMC)
Hyaluronic acid efficacy in root coverage procedures: a systematic review and meta-analysis.
Talebi Ardakani Mohammadreza, Moscowchi Anahita, Talebi Amir et al. · BMC Oral Health · 2025
PMID: 39844152Meta-AnalysisFull text (PMC)
Efficacy of Injectable Laryngoplasty With Hyaluronic Acid and/or Calcium Hydroxyapatite in the Treatment of Glottic Incompetence. Systematic Review and Meta-analysis.
Henriques Débora Pereira, Martins Regina Helena Garcia, Cataneo Antônio José Maria · J Voice · 2025
PMID: 36804345Meta-Analysis
Hyaluronic acid and urology: a systematic review and meta-analysis.
Roth Bradley J, Hammad Muhammed A M, Sultan Mark I et al. · Sex Med Rev · 2025
PMID: 39238469Meta-Analysis
A systematic review on hyaluronic acid coated nanoparticles: recent strategy in breast cancer management.
Rathore Seema S, Leno Jenita J Josephine, Dotherabandi Manjula · J Biomater Sci Polym Ed · 2025
PMID: 39429014Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Hyaluronic acid (substance)
SNOMED CT
38218009
UMLS CUI
C0020196

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.