Substance / Medication

Ibrutinib

Overview

Active Ingredient
ibrutinib
RxNorm CUI
1442981
Labeler: Pharmacyclics LLCUpdated: 2025-10-21T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

3 trials linked to this intervention

3
Total Trials
1
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of ibrutinib in central nervous system lymphoma: A systematic review and meta-analysis.
Jaradat Jaber H, Alkhawaldeh Ibraheem M, Al-Bojoq Yousef et al. · Crit Rev Oncol Hematol · 2025
PMID: 39689737Meta-Analysis
Real world results of ibrutinib in patients with relapsed or refractory chronic lymphocytic leukemia: a meta-analysis of clinical studies.
Karimi Mohammad Amin, Norooziseyedhosseini Hanieh, Khademi Reza et al. · BMC Pharmacol Toxicol · 2025
PMID: 40001241Meta-AnalysisFull text (PMC)
Efficacy, Safety, and Quality-of-Life Outcomes of Remibrutinib in Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis.
Khan Ahmed Ali, Riaz Abdul Ahad, Naseer Faisal et al. · J Allergy Clin Immunol Pract · 2025
PMID: 41005705Meta-Analysis
Safety and Efficacy of Remibrutinib for Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis.
Burhan Muhammad, Ashraf Saad, Ali Ahila et al. · Int Arch Allergy Immunol · 2025
PMID: 40911497Meta-Analysis
Efficacy and Safety of Ibrutinib for Chronic Graft-Versus-Host Disease: A Systematic Review.
Santosa Damai, Rizky Daniel, Tandarto Kevin et al. · Asian Pac J Cancer Prev · 2023
PMID: 38156834Meta-AnalysisFull text (PMC)
Ibrutinib and tracheal mucormycosis: A case report and systematic review of literature.
Damaraju Vikram, Agarwal Ritesh, Singh Sehgal Inderpaul et al. · J Mycol Med · 2023
PMID: 37523991Meta-Analysis
Efficacy and safety of ibrutinib in mantle cell lymphoma: A systematic review and meta-analysis.
Roufarshbaf Mohammad, Javeri Mohsen, Akbari Vajihe et al. · Daru · 2022
PMID: 36057010Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ibrutinib (substance)
SNOMED CT
710228002
UMLS CUI
C3501358
RxNorm CUI
1442981
Labeler
Pharmacyclics LLC

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.