Substance / Medication

Ibuprofen lysine

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

38 trials linked to this intervention

38
Total Trials
11
Recruiting
15
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of Ibuprofen Lysine on First-Trimester AbortionRelated Pain and Hemorrhage: A Randomized TripleBlinded Clinical Trial.
Najmi Zahra, Dabiri Oskoei Atousa, Tofighi Shabnam et al. · Arch Iran Med · 2023
PMID: 38301081RCTFull text (PMC)
Repeated bowel perforations with Ibuprofen lysine: a case report.
Peitz Gregory J, Hoie Eric B, Hoy Shannon et al. · J Pediatr Pharmacol Ther · 2008
PMID: 23055878Case ReportFull text (PMC)
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai Vinita B, Sakadjian Arpi, Puthoff Teresa D · Pharmacotherapy · 2008
PMID: 18752387Review
Ibuprofen lysine salt complexed with β-cyclodextrin oral suspension: an innovative pediatric formulation with clinical advantages.
Ciprandi Giorgio, Badolato Raffaele, Esposito Susanna et al. · Minerva Pediatr (Torino) · 2025
PMID: 40531543Other
Reversibly changing a painkiller structure: a hot topic for a cold case--ibuprofen lysine salt.
Vladiskovic Chiara, Masciocchi Norberto · J Pharm Biomed Anal · 2015
PMID: 25659531Other
Characterization of alginate beads loaded with ibuprofen lysine salt and optimization of the preparation method.
Caballero F, Foradada M, Miñarro M et al. · Int J Pharm · 2014
PMID: 24177314Other
Physical Compatibility of Ibuprofen Lysine Injection with Selected Drugs During Simulated Y-site Injection.
Holt Robert J, Siegert Scott W K, Krishna Aravind · J Pediatr Pharmacol Ther · 2008
PMID: 23055876OtherFull text (PMC)
Ibuprofen lysine (NeoProfen) for the treatment of patent ductus arteriosus.
Poon Grace · Proc (Bayl Univ Med Cent) · 2007
PMID: 17256050OtherFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ibuprofen lysine (substance)
SNOMED CT
425516000
UMLS CUI
C0074814

Clinical Data

This intervention maps to 14 entities in the Healos knowledge graph.

9
Conditions
2
Biomarkers
1
Specialists
0
Symptoms
38
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.