Substance / Medication

Imipramine

Overview

Active Ingredient
imipramine
RxNorm CUI
5691

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

4 trials linked to this intervention

4
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Imipramine for neuropathic pain in adults.
Hearn Leslie, Derry Sheena, Phillips Tudor et al. · Cochrane Database Syst Rev · 2014
PMID: 24838845Meta-AnalysisFull text (PMC)
A prospective and randomized study comparing the use of alarms, desmopressin and imipramine in the treatment of monosymptomatic nocturnal enuresis.
Mello Marcos Figueiredo, Locali Rafael Fagionato, Araujo Rogerio Mattos et al. · J Pediatr Urol · 2023
PMID: 36717289RCT
Effect of imipramine on urethral opening pressure: A randomized, double-blind, placebo-controlled crossover study in healthy women.
Kornholt Jonatan, Sonne David Peick, Riis Troels et al. · Neurourol Urodyn · 2019
PMID: 30843263RCT
Effect of Low Dose Imipramine in Patients with Nocturnal Enuresis, A Randomized Clinical Trial.
Ravanshad Yalda, Azarfar Anoush, Esmaeeli Mohammad et al. · Iran J Kidney Dis · 2019
PMID: 31422392RCT
Effect of single-dose imipramine on chronic low-back and experimental pain. A randomized controlled trial.
Schliessbach Jürg, Siegenthaler Andreas, Bütikofer Lukas et al. · PLoS One · 2018
PMID: 29742109RCTFull text (PMC)
Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial.
Cheong Pui Kuan, Ford Alexander C, Cheung Cynthia K Y et al. · Lancet Gastroenterol Hepatol · 2018
PMID: 30361080RCT
The Impact of Serum Drug Concentration on the Efficacy of Imipramine, Pregabalin, and their Combination in Painful Polyneuropathy.
Sindrup Søren H, Holbech Jakob V, Bach Flemming W et al. · Clin J Pain · 2017
PMID: 28272120RCT
Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn: A Randomized Placebo-Controlled Trial.
Limsrivilai Julajak, Charatcharoenwitthaya Phunchai, Pausawasdi Nonthalee et al. · Am J Gastroenterol · 2016
PMID: 26753892RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Imipramine (substance)
SNOMED CT
372718005
UMLS CUI
C0020934
RxNorm CUI
5691

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

4
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.