Substance / Medication

Infliximab

Overview

Active Ingredient
infliximab
RxNorm CUI
191831
Labeler: Janssen Biotech, Inc.Updated: 2026-02-11T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Warnings and Precautions (5.5) Adverse Reactions (6.1) [seeand] The use of Infliximab at doses >5 mg/kg is contraindicated in patients with moderate or severe heart failure. Warnings and Precautions (5.7) Adverse Reactions (6.1) [seeand]. Infliximab is contraindicated in patients with a previous sev

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

84 trials linked to this intervention

84
Total Trials
30
Recruiting
15
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Clinical and Biochemical Factors Associated With Infliximab Pharmacokinetics in Adult Patients With Inflammatory Bowel Disease.
Pool Ilse A, Volkerink Ilse, Stavast Mirthe et al. · J Clin Pharmacol · 2026
PMID: 40996357Meta-AnalysisFull text (PMC)
Clinical Efficacy of Biosimilar Switch of Adalimumab and Infliximab for Noninfectious Uveitis: Systematic Review and Meta-Analysis.
Zhang Charles, Ayoubi Mohammad, Aboukasm Georges et al. · Am J Ophthalmol · 2026
PMID: 41265720Meta-Analysis
Immunogenicity and Efficacy of Subcutaneous Infliximab Monotherapy vs Combination Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
Anjie Suzanne I, Gecse Krisztina B, Meloni Chiara M et al. · Clin Gastroenterol Hepatol · 2026
PMID: 40378993Meta-Analysis
The efficacy of CT-P13, a biosimilar of infliximab, in inflammatory bowel diseases: a systematic review and meta-analysis.
Hu Xinyue, Tang Xiaowei, Li Limin et al. · BMC Gastroenterol · 2024
PMID: 39533176Meta-AnalysisFull text (PMC)
Reactive Immunomodulator Addition to Infliximab Monotherapy Restores Clinical Response in Inflammatory Bowel Disease: A Meta-Analysis.
Lowell Jeffrey A, Sharma Garvita, Chua Vincent et al. · Dig Dis Sci · 2024
PMID: 38877332Meta-Analysis
Efficacy and safety of infliximab in the treatment of Kawasaki disease: A systematic review and meta-analysis.
Wang Lihe, He Milan, Wang Wei et al. · Eur J Pediatr · 2024
PMID: 38240765Meta-Analysis
Infliximab for parenchymal neuro-Behçet's syndrome: case series and meta-analysis.
Wang Xiaoou, Liu Yeling, Ao Yiyuan et al. · Clin Exp Rheumatol · 2024
PMID: 38757293Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Infliximab (substance)
SNOMED CT
386891004
UMLS CUI
C0666743
RxNorm CUI
191831
Labeler
Janssen Biotech, Inc.

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

5
Conditions
2
Biomarkers
1
Specialists
0
Symptoms
84
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.