Substance / Medication

Iodine

Overview

Active Ingredient
iodine
RxNorm CUI
5933

Indications

® VitafolOne is indicated to provide vitamin, mineral, and omega-3 fatty acid supplementation prior to conception, throughout pregnancy, and during the postnatal period for the lactating and non-lactating mother, including individuals with known allergies to fish.*

Labeler: Exeltis USA, Inc.Updated: 2025-03-20T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or a Poison Control Center immediately.

Contraindications

When this intervention should not be used

® VitafolOne is contraindicated in patients with hypersensitivity to any of its components or color additives. Folic acid is contraindicated in patients with untreated and uncomplicated pernicious anemia, and in those with anaphylactic sensitivity to folic acid. Iron therapy is contraindicated in

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
The effect of iodine solution in total thyroidectomy for patients with Graves disease: A meta-analysis.
Haroon Aslam Mohamed, Ghani Ahmed, Ayesh Abdullah R et al. · Surgery · 2026
PMID: 41351925Meta-Analysis
Effect of radioactive iodine therapy on hematological parameters in patients with thyroid cancer: systematic review and meta-analysis.
Berta Dereje Mengesha, Teketelew Bisrat Birke, Cherie Negesse et al. · Front Endocrinol (Lausanne) · 2025
PMID: 40162306Meta-AnalysisFull text (PMC)
Efficacy and Safety of Targeted Therapy for Radioiodine-Refractory Differentiated Thyroid Cancer.
Zhang Yuqing, Zhang Xiaoxin, Lin Lifan et al. · J Clin Endocrinol Metab · 2025
PMID: 39292866Meta-Analysis
Effect of a topical antibiotic and povidone-iodine vs povidone-iodine alone on conjunctival flora:systematic review and meta-analysis.
Rees Amelia Charlotte, Saleki Mohammad · J Cataract Refract Surg · 2025
PMID: 39957051Meta-Analysis
Diagnostic accuracy of late iodine enhancement on cardiac CT for myocardial tissue characterization: a systematic review and meta-analysis.
Gatti Marco, De Filippo Ovidio, Cura Curà Gaia et al. · Eur Radiol · 2025
PMID: 39702631Meta-Analysis
Contact dermatitis secondary to povidone-iodine: A systematic review.
Kennedy Harriet · Contact Dermatitis · 2025
PMID: 39422398Meta-Analysis
Chlorhexidine Compared with Povidone-Iodine in Intravitreal Injection: A Systematic Review and Meta-Analysis.
Cruz Matheus Ribeiro Barbosa, Amaral Dillan Cunha, Gonçalves Ocílio Ribeiro et al. · J Ocul Pharmacol Ther · 2025
PMID: 39836046Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Iodine (substance)
SNOMED CT
44588005
UMLS CUI
C0021968
RxNorm CUI
5933
Labeler
Exeltis USA, Inc.

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

5
Conditions
1
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.