Substance / Medication

Isoflurane

Overview

Active Ingredient
isoflurane
RxNorm CUI
6026

Indications

Isoflurane, USP liquid for inhalation may be used for induction and maintenance of general anesthesia. Adequate data have not been developed to establish its application in obstetrical anesthesia.

Labeler: Shandong New Time Pharmaceutical Co., Ltd.Updated: 2026-01-05T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Isoflurane, USP liquid for inhalation is contraindicated in patients: in whom general anesthesia is contraindicated. [see Warnings and Precautions (5.3)] with known sensitivity to isoflurane, USP liquid for inhalation or to other halogenated agents. [see Warnings and Precautions (5.1), Clinical Pha

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

15 trials linked to this intervention

15
Total Trials
1
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A health-based recommended occupational exposure limit for isoflurane and sevoflurane using experimental animal data based on a systematic review and dose-response analysis.
Ryan Keanu, Hooijmans Carlijn R, Struijs Fréderique et al. · Environ Toxicol Pharmacol · 2026
PMID: 41453697Meta-Analysis
A systematic review of sevoflurane and isoflurane minimum alveolar concentration in domestic cats.
Shaughnessy Mike R, Hofmeister Erik H · Vet Anaesth Analg · 2014
PMID: 24034181Meta-Analysis
The effect of isoflurane on survival and myocardial infarction: a meta-analysis of randomized controlled studies.
Bignami Elena, Greco Teresa, Barile Luigi et al. · J Cardiothorac Vasc Anesth · 2013
PMID: 22819469Meta-Analysis
Meta-analysis of average and variability of time to extubation comparing isoflurane with desflurane or isoflurane with sevoflurane.
Agoliati Andrew, Dexter Franklin, Lok Jason et al. · Anesth Analg · 2010
PMID: 20418303Meta-Analysis
Haemodynamic changes with Isoflurane and Propofol during Spine Surgery under General Anaesthesia: A Comparative Study.
Mazumder P, Jahan A B M, Sazu M H et al. · Mymensingh Med J · 2026
PMID: 41474912RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Isoflurane (substance)
SNOMED CT
387368002
UMLS CUI
C0022180
RxNorm CUI
6026
Labeler
Shandong New Time Pharmaceutical Co., Ltd.

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

2
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
15
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.