Substance / Medication

Itraconazole

Overview

Active Ingredient
itraconazole
RxNorm CUI
28031

Indications

® immunocompromised and non-immunocompromised SPORANOX(itraconazole) Capsules are indicated for the treatment of the following fungal infections inpatients: Specimens for fungal cultures and other relevant laboratory studies (wet mount, histopathology, serology) should be obtained before therapy to isolate and identify causative organisms. Therapy may be instituted before the results of the cultures and other laboratory studies are known; however, once these results become available, antiinfecti

Labeler: Janssen Pharmaceuticals, Inc.Updated: 2026-01-22T00:00:00.000ZFull label on DailyMed

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

13 trials linked to this intervention

13
Total Trials
4
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Single Use of Itraconazole Has No Effect on Treatment for Penicillium Marneffei with HIV Infection.
Su Qingfeng, Ying Gu, Liang Hao et al. · Arch Iran Med · 2015
PMID: 26161709Meta-Analysis
Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: evidence from a meta-analysis of 3,597 patients.
Glasmacher Axel, Prentice Archibald, Gorschlüter Marcus et al. · J Clin Oncol · 2003
PMID: 14673051Meta-Analysis
Comparative Efficacy of Three Oral Itraconazole Formulations in Superficial Dermatophytosis.
Tyagi Harsh, Goel Shitij, Puri Aneesha et al. · Mycoses · 2025
PMID: 40536246RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Itraconazole (substance)
SNOMED CT
387532006
UMLS CUI
C0064113
RxNorm CUI
28031
Labeler
Janssen Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 15 entities in the Healos knowledge graph.

15
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
13
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.