Substance / Medication

Lepirudin

Overview

Active Ingredient
lepirudin
RxNorm CUI
237057

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Evaluation of a standardized protocol using lepirudin or argatroban for heparin-induced thrombocytopenia.
Kennedy Kenneth, Steinke Doug, King Shawn et al. · Cardiovasc Hematol Agents Med Chem · 2011
PMID: 21902659Trial
Lepirudin: is the approved dosing schedule too high?
Hacquard M, de Maistre E, Lecompte T · J Thromb Haemost · 2005
PMID: 16241965Trial
Use of lepirudin during percutaneous vascular interventions in patients with heparin-induced thrombocytopenia.
Cochran Kevin, DeMartini Tony J, Lewis Bruce E et al. · J Invasive Cardiol · 2003
PMID: 14608129Trial
Point of care measurement of lepirudin and heparin anticoagulation during systemic inflammation.
Homoncik Monika, Pernerstorfer Thomas, Reiter Rosemarie et al. · Thromb Res · 2002
PMID: 12586138Trial
[Removal of lepirudin used as an anticoagulant in mechanical autotransfusion with Cell-Saver 5].
Marx A, von Lüpke U, Tessmann R et al. · Anasthesiol Intensivmed Notfallmed Schmerzther · 2001
PMID: 11324348Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lepirudin (substance)
SNOMED CT
386955005
UMLS CUI
C0772394
RxNorm CUI
237057

Clinical Data

This intervention maps to 10 entities in the Ltrl knowledge graph.

4
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.