Substance / Medication

Lesinurad

Overview

Active Ingredient
lesinurad
RxNorm CUI
1731031

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

17 trials linked to this intervention

17
Total Trials
4
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor.
Shen Zancong, Lee Caroline A, Valdez Shakti et al. · Clin Pharmacol Drug Dev · 2019
PMID: 30748125RCT
Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers.
Shen Zancong, Lee Caroline A, Wallach Kathleen et al. · Clin Pharmacol Drug Dev · 2019
PMID: 30758919Trial
Metabolism and disposition of lesinurad, a uric acid reabsorption inhibitor, in humans.
Shah Vishal, Yang Chun, Shen Zancong et al. · Xenobiotica · 2019
PMID: 30117757Trial
The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.
Baumgartner Scott, Yeh Li-Tain, Shen Zancong et al. · J Clin Pharmacol · 2018
PMID: 29733441TrialFull text (PMC)
Lesinurad for the treatment of hyperuricaemia in people with gout.
Robinson Philip C, Dalbeth Nicola · Expert Opin Pharmacother · 2017
PMID: 29103339Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lesinurad (substance)
SNOMED CT
715259003
UMLS CUI
C3886073
RxNorm CUI
1731031

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
17
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.