Substance / Medication

Lindane

Overview

Active Ingredient
lindane
RxNorm CUI
1388

Indications

Pediculosis humanis capitis Pthirus pubis Lindane Shampoo is indicated for the treatment of head lice (infestations of), crab lice (infestations of), and their ova only in patients who Lindane Shampoo should be used in the context of an overall lice management program that includes: Caregivers applying this product to patients should wear gloves less permeable to Lindane such as nitrile, latex with neoprene or sheer vinyl, and thoroughly clean hands after application. Natural latex gloves should

Labeler: VersaPharm IncorporatedUpdated: 2011-12-13T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

INDICATIONS AND USAGE Lindane Shampoo should only be used in patients who cannot tolerate or have failed first-line treatment with safer medications for the treatment of lice. (See.) Neurologic Toxicity Seizures and deaths have been reported following Lindane Shampoo use with repeat or prolonged app

Contraindications

When this intervention should not be used

Lindane Shampoo is contraindicated for premature infants because their skin may be more permeable than that of full term infants and their liver enzymes may not be sufficiently developed to metabolize Lindane. Lindane Shampoo is also contraindicated for patients with crusted (Norwegian) scabies and

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

8 trials linked to this intervention

8
Total Trials
3
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Ivermectin vs. lindane in the treatment of scabies.
Goldust Mohamad, Rezaee Elham, Raghifar Ramin et al. · Ann Parasitol · 2013
PMID: 23829057RCT
Comparison of oral ivermectin vs. lindane lotion 1% for the treatment of scabies.
Mohebbipour A, Saleh P, Goldust M et al. · Clin Exp Dermatol · 2013
PMID: 23772999RCT
A comparison of the effects of lindane and FeCl/ADP on spontaneous contractions in isolated rat or human term myometrium.
Fanning Rebecca A, Campion Deirdre P, O'Shea Maeve et al. · Reprod Toxicol · 2017
PMID: 28970134Observational
Comparison of Lindane and Carbaryl Pesticide Bioaccumulation in the Common Sole (Solea solea).
Emanuela Frapiccini, Giuseppe Scarcella, Stefano Guicciardi et al. · Bull Environ Contam Toxicol · 2017
PMID: 28289805Observational
Spatial distribution of Lindane concentration in topsoil across France.
Orton T G, Saby N P A, Arrouays D et al. · Sci Total Environ · 2013
PMID: 23202380Observational
Treatment of scabies: comparison of ivermectin vs. lindane lotion 1%.
Mohebbipour Alireza, Saleh Parviz, Goldust Mohamad et al. · Acta Dermatovenerol Croat · 2012
PMID: 23317486Observational
Comparative bioremediation potential of four rhizospheric microbial species against lindane.
Abhilash P C, Srivastava Shubhi, Singh Nandita · Chemosphere · 2011
PMID: 21044795Observational
A comparative study of gene expression profiles in rat liver after administration of alpha-hexachlorocyclohexane and lindane.
Sumida Kayo, Saito Koichi, Oeda Kenji et al. · J Toxicol Sci · 2007
PMID: 17785943Observational
A comparison of European and North American atmospheric deposition networks: polycyclic aromatic hydrocarbons and lindane.
Blanchard Pierrette, Kallweit Dagmar, Brice Kenneth A et al. · J Environ Monit · 2006
PMID: 16604236Observational
Low level lindane exposure alters extinction of conditioned fear in rats.
Cloutier Sylvie, Forquer Melissa R, Sorg Barbara A · Toxicology · 2006
PMID: 16213647Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lindane (substance)
SNOMED CT
77496001
UMLS CUI
C0005038
RxNorm CUI
1388
Labeler
VersaPharm Incorporated

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
8
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.