Substance / Medication

Lithium

Overview

Active Ingredient
lithium
RxNorm CUI
6448

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

34 trials linked to this intervention

34
Total Trials
6
Recruiting
12
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The effects of Lithium on Beta-amyloid deposition and tau phosphorylation: A systematic review.
Xiao Kelei, Sayed Hisham, Xing Jason et al. · J Affect Disord · 2026
PMID: 41260370Meta-Analysis
Determining the best dose of lithium carbonate as adjuvant therapy to radioactive iodine for the treatment of hyperthyroidism: a systematic review and meta-analysis.
Abd-ElGawad Mohamed, Abdelgalil Mahmoud Shaaban, Mabrouk Manar et al. · BMC Endocr Disord · 2025
PMID: 40410789Meta-AnalysisFull text (PMC)
ENaC inhibitors for the management of lithium related polyuria: a systematic review.
Strawbridge Rebecca, Ott Michael, Werneke Ursula et al. · J Affect Disord · 2025
PMID: 40449743Meta-Analysis
The impact of menstrual cycle on the pharmacokinetics of antiseizure medications and lithium: a systematic review and meta-analysis.
Gillessen Maximilian, Schmidt Chiara Theresa, Deligiannidis Kristina M et al. · Expert Opin Drug Metab Toxicol · 2025
PMID: 39964299Meta-Analysis
Persistence of Lithium Underutilization in Patients of African Ancestry with Bipolar Disorder.
Taylor-Desir Monica J, Sanchez-Ruiz Jorge A, Vallender Eric J et al. · Psychopharmacol Bull · 2025
PMID: 39744413Meta-AnalysisFull text (PMC)
Lithium and lamotrigine for the treatment of bipolar II disorder - a systematic review and meta-analysis of randomized trials.
Fredskild Mette Ungermann, Bruun Caroline Fussing, Vinberg Maj et al. · J Affect Disord · 2025
PMID: 40288449Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lithium (substance)
SNOMED CT
85899009
UMLS CUI
C0023870
RxNorm CUI
6448

Clinical Data

This intervention maps to 12 entities in the Healos knowledge graph.

4
Conditions
5
Biomarkers
2
Specialists
0
Symptoms
34
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.