Substance / Medication

Losartan potassium

SNOMED 108582002 UMLS C0700492

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

High blood pressure

Left ventricular hypertrophy

Heart failure

Diabetic renal disease

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Creatinine

LOINC 2160-0

secondary

Potassium

LOINC 2823-3

secondary

Natriuretic peptide.B

LOINC 30934-4

primary

Natriuretic peptide.B prohormone N-Terminal

LOINC 33762-6

primary

Research Evidence

Published studies and systematic reviews

Sort:

Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis.

Feng Pan-Feng, Chen Xiang-Fan, Sheng Nan et al. · PLoS One · 2022

PMID: 36215266Meta-AnalysisFull text (PMC)

[Jinshuibao capsule combined losartan potassium intervened early renal damage of hypertension patients of yin and yang deficiency: a clinical research].

Zhang Cheng-Qiu, Yin Ji-Qing, Xin Qing et al. · Zhongguo Zhong Xi Yi Jie He Za Zhi · 2013

PMID: 23980348RCT

Efficacy/safety of olmesartan medoxomil versus losartan potassium in naïve versus previously treated subjects with hypertension.

Punzi Henry A, Lewin Andrew, Li Wei et al. · Adv Ther · 2012

PMID: 22763801RCT

Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicenter, Phase III Study.

Hong Soon Jun, Jeong Han Saem, Han Seung Hwan et al. · Clin Ther · 2017

PMID: 28939406Trial

Use of 24-hour ambulatory blood pressure monitoring to assess antihypertensive efficacy: a comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan.

Smith David H G, Dubiel Robert, Jones Michael · Am J Cardiovasc Drugs · 2005

PMID: 15631537Trial

Serum concentration of potassium in chronic heart failure patients administered spironolactone plus furosemide and either enalapril maleate, losartan potassium or candesartan cilexetil.

Saito M, Takada M, Hirooka K et al. · J Clin Pharm Ther · 2005

PMID: 16336294Trial

[Efficacy of losartan potassium and its combination with hydrochlorothiazide in hypertensive disease. Focus on the state of microcirculation].

Podzolkov V I, Son E A, Bulatov V A et al. · Kardiologiia · 2003

PMID: 14989241Trial

The effect of losartan potassium on choroidal hemodynamics in healthy subjects.

Spicher Tatiana, Orgül Selim, Gugleta Konstantin et al. · J Glaucoma · 2002

PMID: 12140392Trial

Evaluation of efficacy and safety of losartan potassium in the treatment of mild to moderate hypertension as compared to enalapril maleate.

Shobha J C, Kumar T R, Raju B S et al. · J Assoc Physicians India · 2000

PMID: 11273142Trial

Effect of oral losartan potassium administration on intraocular pressure in normotensive and glaucomatous human subjects.

Costagliola C, Verolino M, De Rosa M L et al. · Exp Eye Res · 2000

PMID: 10930321Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Internal Medicine Physician

Internal Medicine

NUCC 207R00000X

Cardiovascular Disease Physician

Internal Medicine — Cardiovascular Disease

NUCC 207RC0000X

Find a Provider

Health Goals

Goals connected through associated conditions

Improve Cardiovascular Fitness

Quick Facts

Type: Substance / Medication
Fully Specified Name: Losartan potassium (substance)
SNOMED CT: 108582002
UMLS CUI: C0700492

Clinical Data

This intervention maps to 11 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.