Substance / Medication

Luspatercept

Overview

Active Ingredient
luspatercept
RxNorm CUI
2262544
Labeler: Celgene CorporationUpdated: 2024-05-17T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Luspatercept for patients with lower-risk myelodysplastic syndromes/neoplasms: a systematic review and meta-analysis.
Alhajahjeh Abdulrahman, Woite Naira Link, Rolles Benjamin et al. · Blood Adv · 2025
PMID: 40966428Meta-AnalysisFull text (PMC)
Real-life experience of luspatercept in transfusion-dependent lower risk myelodysplastic syndrome patients.
Bouchla Anthi, Papageorgiou Sotirios G, Kotsianidis Ioannis et al. · Br J Haematol · 2025
PMID: 40325906ObservationalFull text (PMC)
Safety and efficacy of luspatercept for the treatment of anemia in patients with myelofibrosis.
Gerds Aaron T, Harrison Claire, Kiladjian Jean-Jacques et al. · Blood Adv · 2024
PMID: 38820422ObservationalFull text (PMC)
Treatment of myelofibrosis with refractory anemia with luspatercept: a multicenter Chinese study.
Wang Leyu, Fang Liwei, Shi Hongxia et al. · Ann Hematol · 2024
PMID: 38907072Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Luspatercept (substance)
SNOMED CT
830158005
UMLS CUI
C4086553
RxNorm CUI
2262544
Labeler
Celgene Corporation

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

1
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.