Substance / Medication

Magnesium hydroxide

Overview

Active Ingredient
magnesium hydroxide
RxNorm CUI
6581
Labeler: Santarus, Inc.Updated: 2006-06-08T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

ZEGERID with Magnesium Hydroxide is contraindicated in patients with known hypersensitivity to any components of the formulation.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Sennosides vs magnesium hydroxide vs polyethylene glycol as a treatment for constipation in anorectal malformation: a randomized crossover trial.
Nate-Anong Butsarin, Khorana Jiraporn, Chantakhow Sireekarn et al. · Pediatr Surg Int · 2025
PMID: 40856829RCT
Magnesium hydroxide-based dentifrice as an anti-erosive agent in an in situ intrinsic erosion model.
Passos Vanara Florêncio, Rodrigues Gerage Lidiany Karla, Lima Santiago Sérgio · Am J Dent · 2017
PMID: 29178758RCT
The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics.
Martin Paul D, Schneck Dennis W, Dane Aaron L et al. · Curr Med Res Opin · 2008
PMID: 18355422RCT
Pharmacokinetic Profile of Oral Magnesium Hydroxide.
Dolberg Mette Konow Bøgebjerg, Nielsen Lars Peter, Dahl Ronald · Basic Clin Pharmacol Toxicol · 2017
PMID: 27412366Trial
Lack of effect of omeprazole or of an aluminium hydroxide/magnesium hydroxide antacid on the pharmacokinetics of lumiracoxib.
Scott Graham, Vinluan Reynolds Christine, Milosavljev Slavica et al. · Clin Pharmacokinet · 2004
PMID: 15080766Trial
Magnesium hydroxide in ibuprofen tablet reduces the gastric mucosal tolerability of ibuprofen.
Mäenpää Jukka, Tarpila Anneli, Jouhikainen Taneli et al. · J Clin Gastroenterol · 2004
PMID: 14679326Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Magnesium hydroxide (substance)
SNOMED CT
387337001
UMLS CUI
C0024476
RxNorm CUI
6581
Labeler
Santarus, Inc.

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

9
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.