Substance / Medication

Maprotiline

Overview

Active Ingredient
maprotiline
RxNorm CUI
6646

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

59 trials linked to this intervention

59
Total Trials
5
Recruiting
19
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.
Pettersen Vera L A, Zapata-Sudo Gisele, Raimundo Juliana M et al. · Anesth Analg · 2009
PMID: 19762762Observational
Effects of antidepressants maprotiline and fluxilan on sympatho-adrenomedullary system in stressed rats.
Spasojevic Natasa, Gavrilovic Ljubica, Kovacevic Ivan et al. · Auton Neurosci · 2009
PMID: 19083273Observational
Comparisons of glucose-insulin homeostasis following maprotiline and fluoxetine treatment in depressed males.
Chen Yi-Chyan, Shen Yu-Chih, Hung Yi-Jen et al. · J Affect Disord · 2007
PMID: 17320192Observational
Acute effects of maprotiline on learning, anxiety, activity and analgesia in male and female mice.
Vinader-Caerols Concepción, Martos Ana Josefa, Monleón Santiago et al. · Acta Neurobiol Exp (Wars) · 2006
PMID: 16617674Observational
Are the effects of the antidepressants amitriptyline, maprotiline, and fluoxetine on inhibitory avoidance state-dependent?
Arenas M Carmen, Vinader-Caerols Concepción, Monleón Santiago et al. · Behav Brain Res · 2006
PMID: 16159672Observational
Inhibition of cardiac HERG potassium channels by antidepressant maprotiline.
Ferrer-Villada Tania, Navarro-Polanco Ricardo A, Rodríguez-Menchaca Aldo A et al. · Eur J Pharmacol · 2006
PMID: 16423345Observational
Effect of maprotiline on Ca(2+) movement in human neuroblastoma cells.
Hsu Shu-Shong, Chen Wei-Chuan, Lo Yuk-Keung et al. · Life Sci · 2004
PMID: 15207657Observational
[Comparative study of electro-acupuncture and maprotiline in treating depression].
Han Cui, Li Xue-wu, Luo He-chun · Zhongguo Zhong Xi Yi Jie He Za Zhi · 2002
PMID: 12592685Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Maprotiline (substance)
SNOMED CT
387180003
UMLS CUI
C0024778
RxNorm CUI
6646

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

5
Conditions
3
Biomarkers
1
Specialists
0
Symptoms
59
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.