Substance / Medication

Memantine

Overview

Active Ingredient
memantine
RxNorm CUI
6719

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Effectiveness and Safety of Memantine Add-on Treatment for Refractory Obsessive-Compulsive Disorder: A Meta-Analysis.
Zhang Wenxuan, Zhang Yuhan, Yu Enyan · J Coll Physicians Surg Pak · 2025
PMID: 40235251Meta-Analysis
Can the neuroprotective effects of memantine prevent the complications of brain injuries? A systematic review of animal models.
Mojtahedzadeh Mojtaba, Hassanpour Rezvan, Moradi Moghaddam Omid et al. · Brain Inj · 2025
PMID: 41025739Meta-Analysis
Memantine for the Treatment of Primary Negative Symptoms in Schizophrenia: A Meta-analysis of Randomized Controlled Trials.
Hong Houlin, Donlon Jack, Schaefer Martin et al. · Clin Drug Investig · 2025
PMID: 40748569Meta-Analysis
Efficacy and safety of cholinesterase inhibitors and memantine for cognitive symptoms in patients with Huntington's disease: A systematic review.
Rodrigues Catarina Correia, Carvalho Vanessa, Sotero Filipa Dourado et al. · J Huntingtons Dis · 2025
PMID: 40791064Meta-Analysis
Therapeutic Efficacy and Safety of Memantine for Children and Adults With ADHD With a Focus on Glutamate-Dopamine Regulation: A Systematic Review.
Choi Won-Seok, Wang Sheng-Min, Woo Young Sup et al. · J Clin Psychiatry · 2024
PMID: 39724018Meta-Analysis
Memantine for autism spectrum disorder.
Brignell Amanda, Marraffa Catherine, Williams Katrina et al. · Cochrane Database Syst Rev · 2022
PMID: 36006807Meta-AnalysisFull text (PMC)
Evaluation of memantine's efficacy and safety in the treatment of children with autism spectrum disorder: A systematic review and meta-analysis.
Elnaiem Walaa, Benmelouka Amira Yasmine, Elgendy Ali Mohamed Naguib et al. · Hum Psychopharmacol · 2022
PMID: 35315131Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Memantine (substance)
SNOMED CT
406458000
UMLS CUI
C0025242
RxNorm CUI
6719

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Memantine — Conditions, Biomarkers & Specialists | Healos | Healos