Substance / Medication

Mepenzolate

Overview

Active Ingredient
mepenzolate
RxNorm CUI
107770

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities.
Yamashita Yasunobu, Tanaka Ken-Ichiro, Asano Teita et al. · Bioorg Med Chem · 2014
PMID: 24844758Observational
Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity.
Tanaka Ken-Ichiro, Yamakawa Naoki, Yamashita Yasunobu et al. · Front Pharmacol · 2018
PMID: 29692733OtherFull text (PMC)
Mepenzolate bromide promotes diabetic wound healing by modulating inflammation and oxidative stress.
Zheng Yongjun, Wang Xingtong, Ji Shizhao et al. · Am J Transl Res · 2016
PMID: 27398156OtherFull text (PMC)
Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity.
Yamashita Yasunobu, Tanaka Ken-Ichiro, Yamakawa Naoki et al. · Bioorg Med Chem · 2019
PMID: 31204225Preclinical
Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.
Kurotsu Shota, Tanaka Ken-ichiro, Niino Tomomi et al. · J Pharmacol Exp Ther · 2014
PMID: 24769542Preclinical
Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease.
Tanaka Ken-Ichiro, Ishihara Tomoaki, Sugizaki Toshifumi et al. · Nat Commun · 2013
PMID: 24189798Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mepenzolate (substance)
SNOMED CT
372834001
UMLS CUI
C0360172
RxNorm CUI
107770

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.