Substance / Medication

Nelfinavir

Overview

Active Ingredient
nelfinavir
RxNorm CUI
134527

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

10 trials linked to this intervention

10
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Hepatotoxicity and nelfinavir: a meta-analysis.
Bruno Raffaele, Sacchi Paolo, Maiocchi Laura et al. · Clin Gastroenterol Hepatol · 2005
PMID: 15880318Meta-Analysis
A Multicenter Randomized Controlled Trial To Evaluate the Efficacy and Safety of Nelfinavir in Patients with Mild COVID-19.
Miyazaki Taiga, Hosogaya Naoki, Fukushige Yuri et al. · Microbiol Spectr · 2023
PMID: 37140398RCTFull text (PMC)
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2.
Xu Zhijian, Shi Danrong, Han Jian-Bao et al. · Signal Transduct Target Ther · 2023
PMID: 37095086RCTFull text (PMC)
Influence of CYP2C19 polymorphism on the pharmacokinetics of nelfinavir and its active metabolite.
Damle Bharat D, Uderman Howard, Biswas Pinaki et al. · Br J Clin Pharmacol · 2009
PMID: 19916992RCTFull text (PMC)
Effects of standard and supratherapeutic doses of nelfinavir on cardiac repolarization: a thorough QT study.
Damle Bharat, Fosser Cecilia, Ito Kaori et al. · J Clin Pharmacol · 2009
PMID: 19246729RCT
Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects.
Fang Annie F, Damle Bharat D, LaBadie Robert R et al. · Pharmacotherapy · 2008
PMID: 18154473RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nelfinavir (substance)
SNOMED CT
373445001
UMLS CUI
C0525005
RxNorm CUI
134527

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
10
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.