Substance / Medication

Nivolumab

Overview

Active Ingredient
nivolumab
RxNorm CUI
1597876
Labeler: E.R. Squibb & Sons, L.L.C.Updated: 2025-11-24T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

81 trials linked to this intervention

81
Total Trials
68
Recruiting
9
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The efficacy of Pembrolizumab, Ipilimumab, and Nivolumab monotherapy and combination for colorectal cancer: A systematic review and meta-analysis.
Adrianto Albertus Ari, Riwanto Ignatius, Sadhana Udadi et al. · PLoS One · 2025
PMID: 41237182Meta-AnalysisFull text (PMC)
Can Pembrolizumab or Nivolumab be efficiently used against colorectal cancers with defective mismatch repair and high index of microsatellite instability?
do Nascimento Glauto Tuquarre Melo, Pereira Irislene Costa, de Oliveira Kynnara Gabriella Feitosa et al. · Med Oncol · 2025
PMID: 40591014Meta-Analysis
The efficacy and safety of relatlimab/nivolumab combination therapy in patients with advanced melanoma: a systematic review.
Hasanzadeh Saba, Farokh Parisa, Vazifeh Fatemeh et al. · Arch Dermatol Res · 2024
PMID: 39636334Meta-Analysis
Efficacy and safety of nivolumab plus ipilimumab versus nivolumab alone in patients with advanced melanoma: a systematic review and meta-analysis.
Cui Shuting, Sun Xiaozhe, Gao Junxi · Expert Rev Anticancer Ther · 2024
PMID: 38532600Meta-Analysis
An Efficacy and Safety Comparison of Regorafenib and Nivolumab in Unresectable Hepatocellular Cancer Patients: A Systematic Review.
Darmadi Darmadi, Sungkar Taufik, Pakpahan Cennikon et al. · Acta Med Acad · 2024
PMID: 38984699Meta-AnalysisFull text (PMC)
Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis.
Dai Bowen, Jiang Jiaping, Yu Xiaoyu et al. · Front Oncol · 2024
PMID: 39839773Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nivolumab (substance)
SNOMED CT
704191007
UMLS CUI
C3657270
RxNorm CUI
1597876
Labeler
E.R. Squibb & Sons, L.L.C.

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
81
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.