Substance / Medication

Nystatin

Overview

Active Ingredient
nystatin
RxNorm CUI
7597

Indications

Nystatin Oral Suspension is indicated for the treatment of candidiasis in the oral cavity.

Labeler: Major PharmaceuticalsUpdated: 2026-02-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

The preparation is contraindicated in patients with a history of hypersensitivity to any of its components.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis.
Lyu Xin, Zhao Chen, Yan Zhi-Min et al. · Drug Des Devel Ther · 2016
PMID: 27042008Meta-AnalysisFull text (PMC)
Nystatin prophylaxis and treatment in severely immunodepressed patients.
Gøtzsche Peter C, Johansen Helle Krogh · Cochrane Database Syst Rev · 2014
PMID: 25188770Meta-AnalysisFull text (PMC)
Chemoprophylaxis of neonatal fungal infections in very low birthweight infants: efficacy and safety of fluconazole and nystatin.
Blyth Christopher C, Barzi Federica, Hale Katherine et al. · J Paediatr Child Health · 2012
PMID: 22970680Meta-Analysis
Nystatin prophylaxis and treatment in severely immunodepressed patients.
Gøtzsche P C, Johansen H K · Cochrane Database Syst Rev · 2002
PMID: 12076436Meta-Analysis
Nystatin prophylaxis and treatment in severely immunodepressed patients.
Gøtzsche P C, Johansen H K · Cochrane Database Syst Rev · 2002
PMID: 12519566Meta-Analysis
Nystatin prophylaxis and treatment in severely immunodepressed patients.
Gotzsche P C, Johansen H K · Cochrane Database Syst Rev · 2000
PMID: 10796846Meta-Analysis
Oral nystatin prophylaxis to prevent systemic fungal infection in very low birth weight preterm infants: a randomized controlled trial.
Rundjan Lily, Wahyuningsih Retno, Oeswadi Chrissela Anindita et al. · BMC Pediatr · 2020
PMID: 32303210RCTFull text (PMC)
Effects of Streptococcus salivarius K12 with nystatin on oral candidiasis-RCT.
Hu Lijun, Mao Qinghua, Zhou Peiru et al. · Oral Dis · 2019
PMID: 31177581RCT
Combined vaginal administration of nystatin, diiodohydroxyquin, and benzalkonium chloride versus oral metronidazole for the treatment of bacterial vaginosis.
Chooprasertsuk Wichinee, Somboonporn Woraluk, Soontrapa Sukree et al. · Int J Gynaecol Obstet · 2019
PMID: 30895611RCT
[The clinical research of nystatin in prevention of invasive fungal infections in patients on mechanical ventilation in intensive care unit].
Chen Zhi, Yang Chun-li, He Hui-wei et al. · Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · 2013
PMID: 24021043RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nystatin (substance)
SNOMED CT
387048002
UMLS CUI
C0028741
RxNorm CUI
7597
Labeler
Major Pharmaceuticals

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.