Substance / Medication

Panitumumab

Overview

Active Ingredient
panitumumab
RxNorm CUI
263034
Labeler: Amgen IncUpdated: 2025-06-03T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Dermatologic Toxicity: Dosage and Administration (2.3) Warnings and Precautions (5.1) Adverse Reactions (6.1) [see,and] Dermatologic toxicities occurred in 90% of patients and were severe (NCI-CTC Grade 3 and higher) in 15% of patients receiving Vectibix monotherapy.

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

6 trials linked to this intervention

6
Total Trials
6
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A comparison of panitumumab and cetuximab in the treatment of KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis.
Liu Tong, Jiang Shuai, Teng Xue et al. · Immunopharmacol Immunotoxicol · 2023
PMID: 35950851Meta-Analysis
Chemotherapy plus panitumumab/cetuximab versus chemotherapy plus bevacizumab in wild-type KRAS/RAS metastatic colorectal cancer: a meta-analysis.
Zhang Chengren, Liu Lili, Lv Yaochun et al. · Expert Rev Anticancer Ther · 2022
PMID: 36374121Meta-Analysis
The impact of hepatic and renal function on panitumumab exposures in patients with metastatic RAS wild-type colorectal cancer.
Liao Michael Z, Prenen Hans, Dutta Sandeep et al. · Cancer Chemother Pharmacol · 2021
PMID: 34213592Meta-AnalysisFull text (PMC)
The efficacy and safety of panitumumab supplementation for colorectal cancer: A meta-analysis of randomized controlled studies.
Wang Chengchen, Tan Chunyan, Chen Xiaopin et al. · Medicine (Baltimore) · 2020
PMID: 32176047Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Panitumumab (substance)
SNOMED CT
423259008
UMLS CUI
C0879427
RxNorm CUI
263034
Labeler
Amgen Inc

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
6
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.