Substance / Medication

Papaverine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

118 trials linked to this intervention

118
Total Trials
15
Recruiting
20
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Factor XI as a new target for prevention of thromboembolism in cardiovascular disease: a meta-analysis of randomized controlled trials.
Ali Ahmed E, Awad Mohamed K, Ali Karim et al. · J Thromb Thrombolysis · 2025
PMID: 38762711Meta-Analysis
Bioinformatics Analysis Reveals HIST1H2BH as a Novel Diagnostic Biomarker for Atrial Fibrillation-Related Cardiogenic Thromboembolic Stroke.
Jiang Wenbing, Jiang Lelin, Zhao Xiaoli et al. · Mol Biotechnol · 2025
PMID: 38825608Meta-Analysis
Left atrial appendage occlusion devices vs direct oral anticoagulants for atrial fibrillation: An updated systematic review and meta-analysis.
Fernandes Julia M, Pinheiro Rafael P S, Serpa Frans et al. · Curr Probl Cardiol · 2025
PMID: 39395644Meta-Analysis
Major clinical outcomes in symptomatic vs. asymptomatic atrial fibrillation: a meta-analysis.
Karakasis Paschalis, Pamporis Konstantinos, Siontis Konstantinos C et al. · Eur Heart J · 2025
PMID: 39428997Meta-Analysis
Perioperative direct oral anticoagulant management during cardiac implantable electronic device surgery: an updated systematic review and meta-analysis.
Ezenna Chidubem, Pereira Vinicius, Abozenah Mohammed et al. · J Interv Card Electrophysiol · 2025
PMID: 39546144Meta-Analysis
Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study.
Asgari Seyed Alaeddin, Asli Mani Mohiti, Madani Ali Hamidi et al. · BJU Int · 2012
PMID: 22348304RCT
Role of papaverine hydrochloride administration in patients with intractable renal colic: randomized prospective trial.
Yencilek Faruk, Aktas Can, Goktas Cemal et al. · Urology · 2008
PMID: 18789511RCT
Embolic activity subsequent to injection of the internal mammary artery with papaverine hydrochloride.
Likosky Donald S, Donegan Desmond J, Groom Robert C et al. · Heart Surg Forum · 2005
PMID: 16283980Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Papaverine hydrochloride (substance)
SNOMED CT
40404004
UMLS CUI
C0700461

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

9
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
118
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.