Substance / Medication

Pentamidine isethionate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

3 trials linked to this intervention

3
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of pentamidine isethionate for tegumentary and visceral human leishmaniasis: a systematic review.
Piccica Matteo, Lagi Filippo, Bartoloni Alessandro et al. · J Travel Med · 2021
PMID: 33890115Meta-Analysis
Tsetse fly evolution, genetics and the trypanosomiases - A review.
Krafsur E S, Maudlin Ian · Infect Genet Evol · 2018
PMID: 29885477Meta-Analysis
Major vectors and vector-borne diseases in small ruminants in Ethiopia: A systematic review.
Asmare Kassahun, Abayneh Takele, Sibhat Berhanu et al. · Acta Trop · 2017
PMID: 28212848Meta-Analysis
Prevalence of bovine trypanosomosis in Ethiopia: a meta-analysis.
Leta Samson, Alemayehu Gezahegn, Seyoum Zewdu et al. · Parasit Vectors · 2016
PMID: 26965590Meta-AnalysisFull text (PMC)
A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases.
Isah Murtala Bindawa, Ibrahim Mohammed Auwal, Mohammed Aminu et al. · Parasitology · 2016
PMID: 27240847Meta-Analysis
Diminazene aceturate--An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics.
da Silva Oliveira George Laylson, de Freitas Rivelilson Mendes · Pharmacol Res · 2015
PMID: 26470648Meta-Analysis
Neglected tropical diseases: survey and geometry of randomised evidence.
Kappagoda Shanthi, Ioannidis John P A · BMJ · 2012
PMID: 23089149Meta-AnalysisFull text (PMC)
Treatment of Old World cutaneous leishmaniasis by pentamidine isethionate. An open study of 11 patients.
Hellier I, Dereure O, Tournillac I et al. · Dermatology · 2000
PMID: 10773699Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pentamidine isethionate (substance)
SNOMED CT
16826009
UMLS CUI
C0030864

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.