Substance / Medication

Pheniramine maleate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Urticaria

Nonseasonal allergic rhinitis

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Effects of Chlorpheniramine Maleate on Catheter-Related Bladder Discomfort in Patients Undergoing Ureteroscopic Stone Removal: A Randomized Double-Blind Study.

In Chi-Bum, Lee Seok-Jin, Sung Tae-Yun et al. · Int J Med Sci · 2021

PMID: 33456366RCTFull text (PMC)

Spectrophotometric method development and validation for determination of chlorpheniramine maleate in bulk and controlled release tablets.

Ashfaq Maria, Sial Ali Akber, Bushra Rabia et al. · Pak J Pharm Sci · 2018

PMID: 29386165Observational

Ultraviolet A photosensitivity profile of dexchlorpheniramine maleate and promethazine-based creams: Anti-inflammatory, antihistaminic, and skin barrier protection properties.

Facchini Gustavo, Eberlin Samara, Clerici Stefano Piatto et al. · J Cosmet Dermatol · 2017

PMID: 28593645Observational

Assessment of protective effects of pheniramine maleate on reperfusion injury in lung after distant organ ischemia: a rat model.

Gokalp Orhan, Yurekli Ismail, Kiray Muge et al. · Vasc Endovascular Surg · 2013

PMID: 23377174Observational

Herb-drug pharmacokinetic interaction of artificial calculus bovis with diclofenac sodium and chlorpheniramine maleate in rats.

Peng Can, Lv Mengying, Tian Jixin et al. · J Pharm Pharmacol · 2013

PMID: 23738734Observational

Assessment of protective effects of methylprednisolone and pheniramine maleate on reperfusion injury in kidney after distant organ ischemia: a rat model.

Bayrak Serdar, Yurekli Ismail, Gokalp Orhan et al. · Ann Vasc Surg · 2012

PMID: 22445244Observational

Multivariate optimization and validation of a capillary electrophoresis method for the simultaneous determination of dextromethorphan hydrobromur, phenylephrine hydrochloride, paracetamol and chlorpheniramine maleate in a pharmaceutical preparation using response surface methodology.

Palabiyik I Murat, Onur Feyyaz · Anal Sci · 2010

PMID: 20702938Observational

To evaluate and compare the effects of first generation anti-histamine (chlorpheniramine maleate) and second generation anti-histamine (loratadine) on isolated trachea of rabbit.

Jalbani G A, Aamir K, Shaikh A M et al. · J Pak Med Assoc · 2004

PMID: 15623181Observational

In vitro and ex vivo permeation studies of chlorpheniramine maleate gels prepared by carbomer derivatives.

Taş Cetin, Ozkan Yalcin, Savaşer Ayhan et al. · Drug Dev Ind Pharm · 2004

PMID: 15285337Observational

Development of a validated capillary electrophoresis method for enantiomeric purity testing of dexchlorpheniramine maleate.

Van Eeckhaut Ann, Detaevernier Marc Robert, Michotte Yvette · J Chromatogr A · 2002

PMID: 12134827Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Pheniramine maleate (substance)
SNOMED CT: 116546005
UMLS CUI: C0887016

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.